نوع مقاله : مقاله پژوهشی
نویسندگان
1 دانشجوی کارشناسی ارشد فیزیولوژی فعالیت بدنی و تندرستی، دانشکده علوم انسانی، دانشگاه شاهد، تهران، ایران.
2 استادیار گروه تربیت بدنی و علوم ورزشی، دانشکده علوم انسانی، دانشگاه شاهد، تهران، ایران.
3 استادیار مرکز تحقیقات تنظیم پاسخ های ایمنی، دانشگاه شاهد، تهران، ایران.
چکیده
زمینه و هدف: بر اساس شواهد موجود، فعالیت ورزشی منظم میتواند موجب کاهش التهاب مزمن شود. هدف از تحقیق حاضر بررسی تأثیر 8 هفته تمرین استقامتی بر سطح سرمی اینترلوکین 10 و ترکیب بدنی زنان غیرفعال دارای اضافه وزن بود. روش تحقیق: 22 زن غیرفعال از زنان میانسال شهر پردیس دارای اضافه وزن (25<BMI) به صورت تصادفی در دو گروه تجربی و کنترل قرار گرفتند. برنامه تمرین استقامتی شامل 8 هفته دویدن بر روی نوار گردان با تواتر 3 جلسه در هفته، به مدت 20 تا 30 دقیقه و شدت 50 تا 70 درصد حداکثر ضربان قلب ذخیره بود. ارزیابی های جسمانی و نمونه گیری خونی در حالت ناشتا، 48 ساعت قبل و بعد از برنامه تمرین استقامتی انجام شد. جهت سنجش اینترلوکین 10 از روش الایزا استفاده شد. برای استخراج نتایج از آزمون آنکوا در سطح معنی داری 05/0>p استفاده شد. یافته ها: درصد چربی (002/0=p)، شاخص توده بدنی (01/0=p) و نسبت دور کمر به دور لگن (04/0=p) گروه تجربی نسبت به گروه کنترل کاهش معنی داری نشان داد، در حالیکه توده بدون چربی (11/0=p) و سطح سرمی اینترلوکین 10 (52/0=p) تغییر معنی دار نکرد. نتیجه گیری: فعالیت ورزشی استقامتی از طریق بهبود ترکیب بدنی میتواند نقش مهمی در پیشگیری از ابتلا به بیماری های مرتبط با اضافه وزن و چاقی داشته باشد؛ اما برای برای دست یابی به اثرات ضد التهابی این نوع فعالیت ورزشی، احتمالا به مطالعات بیشتری نیاز است.
کلیدواژه‌ها
عنوان مقاله [English]
The effects of 8 weeks of endurance exercise training on IL-10 level and body composition of sedentary overweight women
نویسندگان [English]
- Elham Shafieerad 1
- Amin Isanejad 2
- Esmaeel Nasiri 3
1 Ms. C Student of Physical Activity and Health Physiology, Physical Education Department, Shahed University, Tehran, Iran.
2 Assistant Professor, Physical Education Department, Shahed University, Tehran, Iran.
3 Immune Regulation Research Center, Shahed University, Tehran, Iran.
چکیده [English]
Background and Aim: According recent evidence, regular exercise training can reduce the chronic inflammation. The
aim of this study was to investigate the effect of 8 weeks of endurance exercise training on serum levels of IL-10 and body composition of sedentary overweight women. Materials and Methods: Twenty tow middle aged overweight (BMI>25 kg/m2) and sedentary women were from Pardis city randomized divided into two groups including control (C) and exercise training (EX) groups. Endurance exercise training group participated in running exercise on a treadmill (three sessions per week) for 8 weeks, 20-30 min per session, at 50-70% their maximal reserve heart rate. Blood samples were collected in fasting state at 48 hours before starting training and 48 hours after last exercise session. IL-10 level were measured ELISA assay. Results were extracted by analysis of covariance (ANCOVA) method at significant level of pResults: Body fat percent (p=0.002), BMI (p=0.01 ) and WHR (p=0.04) of exercise group significantly decreased in compare to control group but there was no significant changes in IL-10 (p=0.52) levels and fat-free mass (p=0.11). Conclusion: Endurance exercise training can play important role in prevention of diseases-induced overweight by improvement of body composition; however it seems that more studies will be needed for obtaining the anti-inflammatory effects of such exercise.
کلیدواژه‌ها [English]
- overweight
- Body composition
- Endurance training
- Interleukin-10
- Inflammation
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