نوع مقاله : مقاله پژوهشی
نویسندگان
1 دانشجوی دکتری فیزیولوژی ورزش، گروه تربیت بدنی و علوم ورزشی، واحد بجنورد، دانشگاه آزاد اسلامی، بجنورد، ایران.
2 استادیار فیزیولوژی ورزش، گروه تربیت بدنی و علوم ورزشی، واحد بجنورد، دانشگاه آزاد اسلامی، بجنورد، ایران.
3 دانشیار گروه ارتوپدی، دانشگاه علوم پزشکی مشهد، مشهد، ایران.
چکیده
زمینه و هدف: مطالعات محدودی اثر تحریک الکتریکی عضله (EMS) بر عوامل رشدی در دوره بازتوانی ورزشکاران بعد از عمل جراحی رباط صلیبی قدامی (ACL) را مورد بررسی قرار داده‌‌اند. هدف از تحقیق حاضر، مقایسه اثر تمرین مقاومتی همراه با EMS و تمرین مقاومتی بر سطوح سرمی گیرنده فعال کننده تکثیر پروکسی زوم گاما هم فعال ساز-1 آلفا (PGC-1α)، عامل رشد شبه انسولین-1 (IGF-1) و مایوستاتین در ورزشکاران مرد پس از جراحی ACL بود. روش تحقیق: تعداد 20 داوطلب مرد با میانگین سنی 12/1±01/26 سال، قد 59/9±10/177 سانتی متر، و وزن 65/6±16/71 کیلو گرم به‌طور تصادفی به دو گروه 10 نفری شامل گروه تمرین مقاومتی همراه با EMS و تمرین مقاومتی تقسیم شدند. آزمودنی‌های هر دو گروه برنامه تمرین مقاومتی را به مدت 12 هفته در سه نوبت با شدت 70-30 درصد 10 تکرار بیشینه انجام دادند. آزمودنی‌های گروه تمرین مقاومتی یه همراه با EMS، حرکات ورزشی را همراه با تحریک الکتریکی با فرکانس 70-35 هرتز به اجرا درآوردند. نمونه‌‌های خونی قبل و 48 ساعت بعد از آخرین جلسه تمرینی از همه آزمودنی‌‌ها اخذ گردید. برای اندازه‌گیری سطوح PGC-1α، IGF-1 و مایوستاتین سرمی از روش الایزا استفاده شد. مقایسه بین گروهی با استفاده از آزمون تحلیل کوواریانس در سطح معنی داری 0/05>p انجام شد. یافته‌ها: در مقایسه با تمرین مقامتی تنها، تمرین مقاومتی همراه با EMS، موجب افزایش معنی دار غلظت سرمی IGF-1 و کاهش معنی دار سطوح سرمی مایوستاتین، بدون تغییر معنی دار در PGC-1α سرمی شرکت‌کنندگان شد. نتیجه‌گیری: تغییرات ایجاد شده در متغیرهای وابسته دال بر آن است که تمرین مقاومتی همراه با EMS در مقایسه با تمرین مقاومتی تنها، منجر به بهبود عوامل حجم دهنده و تقویت کننده عضلات چهار سر ران و همسترینگ ورزشکاران بعد از جراحی ACL می شود و از این روش می توان در دروه بازتوانی ACL استفاده کرد.
کلیدواژه‌ها
عنوان مقاله [English]
The effect of resistance training along with electrical muscle stimulation on serum levels of PGC-1α, IGF-1 and myostatin in athletes after ACL surgery
نویسندگان [English]
- Ali Hoseleh 1
- Ali Yaghoubi 2
- Amir Shahriar Ariamanesha 3
- Najme Rezaeian 2
1 Ph.D Student in Exercise Physiology, Department of Physical Education and Sport Science, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran.
2 Assistant Professor at Department of Physical Education and Sport Science, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran.
3 Associate Professor at Department of Orthopedics, Mashhad University of Medical Sciences, Mashhad, Iran.
چکیده [English]
Background and Aim: Limited studies have investigated the effect of electrical muscle stimulation (EMS) on muscle growth factors in athletes after the anterior cruciate ligament (ACL) rehabilitation. The aim of the present study was to compare the effect of resistance training and resistance training combined with EMS on serum levels of peroxisome proliferator activated receptor-gamma co-activator 1-alpha (PGC-1α), insulin-like growth factor-1 (IGF-1) and myostatin in male athletes after ACL surgery. Materials and Methods: Twenty volunteers with 26.01±1.12 year’s old, 177.10±9.59 cm height and 71.16±6.65 kg weight were randomly divided into two groups including resistance training combined with EMS and resistance training. The subjects in both groups performed three sets of resistance training movements with an intensity of 30-70% of 10 maximum repetitions for 12 weeks. The subjects in the resistance training combined with EMS group performed exercise training with electrical stimulation with a frequency of 35-70 Hz. Blood samples were taken from all subjects before and 48 hours after the last training session. ELISA method was used to measure serum PGC-1α, IGF-1 and myostatin levels. The comparison between groups was done using analysis of covariance test at a significance level of p<0.05. Results: The results showed that 12 weeks of resistance training combined with EMS compare to resistance intervention caused a significant increase in serum IGF-1 concentration and a significant decrease in serum myostatin levels, without significant change in serum PGC-1α of the participants. Conclusion: Overall, resistance training combined with EMS compared to traditional resistance training may lead to changes in serum levels of myostatin and IGF-1, which in turn increases the volume and strength of quadriceps and hamstring athletes after ACL surgery and can be used in ACL rehabilitation period.
کلیدواژه‌ها [English]
- Myostatin
- Peroxisome proliferator activated receptor-gamma co-activator 1-alpha
- Insulin-like growth factor-1
- Exercise training
- Electrical stimulation
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