نوع مقاله : مقاله پژوهشی
نویسندگان
1 استادیار، گروه علوم ورزشی، دانشکده علوم انسانی، دانشگاه آزاد اسلامی واحد اهر، اهر، ایران
2 دانشجوی دکتری، گروه علوم ورزشی، دانشکده علوم تربیتی و روان شناسی، دانشگاه محقق اردبیلی، اردبیل، ایران.
3 مربی، گروه علوم ورزشی، دانشکده علوم انسانی، دانشگاه آزاد اسلامی واحد جلفا، جلفا، ایران.
چکیده
زمینه و هدف: با توجه به اهمیت مصرف آنتی اکسیدان‌های گیاهی در جلوگیری از شاخصهای التهابی و آسیب عضلانی، هدف از مطالعه حاضر بررسی تأثیر مصرف هشت هفته مکمل انار بر شاخصهای التهابی و آسیب عضلانی در مردان دارای اضافه‌وزن غیر ورزشکار بود. روش تحقیق: 20 مرد سالم در یک طرح نیمه تجربی - دوسوکور، به‌صورت تصادفی در دو گروه مکمل انار (10=n) و دارونما (10=n) به مدت هشت هفته، سه جلسه در هفته با شدت 50 تا 80 درصد حداکثر اکسیژن مصرفی (VO2max) دویدند؛ بعد از هشت هفته، تمامی آزمودنیها در آزمونهای ورزشی 60 و 75 (VO2max) شرکت کردند. نمونه خون وریدی در مرحله پایه، بلافاصله بعد و 24 ساعت پس از شدت‌های مختلف فعالیت هوازی، برای اندازه گیری شاخص های التهابی و آسیب عضلانی گرفته شد. از آزمون آماری t همبسته و تحلیل واریانس با اندازه‌گیری مکرر با آزمون تعقیبی بونفرونی استفاده شد. یافته‌ها: میزان عامل نکروز دهنده تومور آلفا (TNF-α) و پروتئین واکنش‌گرC (CRP) در هر دو شدت، بلافاصله پس از فعالیت ورزشی در هر دو گروه مکمل انار و دارونما افزایش معنی‌دار داشت (0/001=p) و میزان TNF-α 24 ساعت پس از فعالیت ورزشی در گروه مکمل و دارونما با هر دو شدت 60 و 75 درصد (VO2max) به ترتیب کاهش معنی‌داری داشت (0/001=p) (p=0/001)، (p=0/01) (p=0/01). و بین گروه‌ها تفاوت معنی‌داری یافت نشد (0/07=P)، ولی شاخص CRP 24 ساعت پس از فعالیت در گروه مکمل در مقایسه با دارونما بویژه، در 75 درصد شدت، کاهش معنی‌داری داشت (0/3=p). با این حال تغییرات کراتین کیناز (CK) در هیچ‌کدام از گروه‌ها در مراحل متفاوت با شدت‌های مختلف 60 و 75 درصد معنی‌دار نبود. نتیجه گیری: مصرف مکمل انار طی هشت هفته فعالیت ورزشی، در کنترل و کاهش شاخصهای التهابی بویژه CRP در افراد سالم موثر نشان داد. با این وجود با توجه به مطالعات اندک در این زمینه، انجام مطالعات بیشتر، ضروری به نظر میرسد.
کلیدواژه‌ها
عنوان مقاله [English]
The effect of 8 week of pomegranate supplementation on inflammatory and muscular damage indices in over weight untrained men due todifferent intensity VO2max
نویسندگان [English]
- Hasan Farhadi 1
- Soheila Rahimi Fardin 2
- Behrouz Baghaiee 3
1 Assistant Professor in Sport Sciences, Ahar Branch, Islamic Azad University, Ahar, Iran.
2 PhD student in Sport Sciences, Department of Sport Sciences, Mohaghegh Ardabil University, Ardabil, Iran.
3 Lectureship in Sport Sciences, Julpha Branch, Islamic Azad University, Julpha, Iran.
چکیده [English]
Background and Aim: Considering the importance of the use of plant antioxidants in preventing inflammatory and muscular damage indices, the present study was performed to determine the effect of 8 weeks of pomegranate supplementation and aerobic training on inflammatory and muscular damage indices in overweight men. Materials and Methods: Twenty overweight men were assigned into two equal supplement and placebo groups as randomized and double-blind study (225mg/day pomegranate or dextrose for 8 week). Meanwhile, both groups participated in running tests with 50 to 80% maximum oxygen consumption (VO2max) 8weeks, 3 sessions/ week. Then, blood samples were taken during three phases at baseline, immediately and 24 hours after different intensities of aerobic exercise (60% and 75% VO2max). The data was analyzed by SPSS software (V: 20) using repeated measure ANOVA and paired T tests at the significant level P≤0.05. Results: The result showed a significant increase in Tumor necrosis factor-alpha and C - reactive protein immediately after the exercise in both groups (P=0.001). However, these indices were decreased 24 hours after exercise in both groups, and this decrement was higher in the pomegranate group (P=0.001), (P=0.01). Although, no significant difference was found in Creatine kinase in any stage of the study in both groups (P=0.27), (P=0.20), but, a significant decrease was found in CRP levels in the supplement group as compared with placebo in 75% VO2max (P=0.03). Conclusion: The results indicated that the combination of regular exercise and pomegranate supplementation had a significant effect on the control and decline of inflammatory markers particularly CRP in overweight males. However, more research is needed based on a few studies conducted in this area.
کلیدواژه‌ها [English]
- Pomegranate supplementation
- inflammatory markers
- muscular damage
- VO2max
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