نوع مقاله : مقاله پژوهشی
نویسندگان
1 کارشناسی ارشد فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه حکیم سبزواری، سبزوار، ایران.
2 دانشیار گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه حکیم سبزواری، سبزوار، ایران.
3 استاد گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه فردوسی مشهد، مشهد، ایران.
4 دانشجوی دکتری فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه حکیم سبزواری، سبزوار، ایران.
چکیده
زمینه و هدف: فعالیت بدنی و برخی آنتی‌اکسیدان ها مانند ویتامین E و C ؛ از عوامل موثر بر سیستم ایمنی هستند. هدف از پژوهش حاضر، بررسی تاثیر چهار هفته تمرین موازی و مصرف ویتامین E و C بر پاسح حاد ایمونوگلوبولین ها و کورتیزول سرم به یک وهله فعالیت هوازی وامانده ساز در زنان غیر فعال بود. روش تحقیق: پژوهش حاضر از نوع نیمه‌تجربی بود. 24 زن به صورت تصادفی به دو گروه مساوی (12 نفر) شامل گروه تمرین موازی (استقامتی و مقاومتی)+ مکمل ویتامینی (E و C)؛ و تمرین موازی (استقامتی و مقاومتی) + دارونما تقسیم شدند. عمل خونگیری قبل و بعد از یک جلسه فعالیت هوازی وامانده‌ساز (فعالیت با شدت 75 درصد حداکثر ضربان قلب ذخیره روی نوارگردان) و پس از اتمام چهار هفته فعالیت موازی به همراه مصرف مکمل؛ انجام گردید. گروه تمرین موازی+ مکمل ویتامینی (E و C)، چهار هفته تمرین موازی (سه جلسه تمرین در هر هفته) انجام دادند و همراه با آن، به مدت 30 روز مکمل ویتامین E و C (500 میلی‌گرم ویتامین C و200 میلی‌گرم ویتامین E، دو بار در روز) مصرف نمودند. کورتیزول و ایمونوگلوبولین‌های سرم به ترتیب با روش گاما و نفلومتری اندازه گیری شدند. برای مقایسه تغییرات قبل و بعد از یک جلسه فعالیت وامانده‌ساز دو گروه، از آزمون تحلیل کوواریانس و برای تعیین اختلاف بین گروهی متغیرها بعد از چهار مرحله اندازه‌گیری، از آزمون تحلیل واریانس با اندازه‌گیری مکرر و آزمون تعقیبی بونفرونی در سطح معنی‌داری 0/05≥p استفاده شد. یافته‌ها: بعد از مداخله، در گروه مکمل ویتامینی (E و C) افزایش معنی داری در میزان IgM (p=0/03) و IgA (p=0/004)؛ و کاهش معنی‌داری در IgG (p=0/007) نسبت به گروه دارونما ایجاد گردید. از طرف دیگر، تفاوت معنی داری در میزان کورتیزول (13/0=p)، قدرت عضلانی بالاتنه (0/31=p) و قدرت عضلانی پایین تنه (0/53=p)، استقامت عضلانی بالاتنه (0/66=p) و حداکثر اکسیژن مصرفی (0/12=p) دو گروه تمرین موازی+مکمل ویتامینی (E و C) و تمرین موازی + دارونما مشاهده نشد؛ در حالی که استقامت عضلانی پایین تنه در تمرین موازی - مکمل به طور معنی داری (0/003=p) افزایش یافت. نتیجه‌گیری: مصرف ویتامین‌های C و E به همراه تمرینات موازی استقامتی و مقاومتی (چهار هفته)، آثار بهینه‌ای بر شاخص‌های ایمنی و آمادگی جسمانی زنان غیر فعال دارد. همچنین با مصرف ویتامین‌های C و E، می‌توان تغییرات حاد در ایمونوگلوبولین‌ها و کورتیزول سرم پس از فعالیت وامانده ساز را بهبود بخشید.
کلیدواژه‌ها
عنوان مقاله [English]
The effect of four weeks of concurrent training and consumption of vitamins E and C on the acute response of serum immunoglobulins and cortisol to an exhaustive aerobic activity
نویسندگان [English]
- Elham Naseri 1
- Roya Askari 2
- Alireza Hosseni kakhk 3
- Halimeh Vahdatpoor 4
1 MSc in Exercise Physiology, Faculty of Sport Sciences, Hakim Sabzevari University, Sabzevar, Iran.
2 Associate Professor, Department of Exercise Physiology, Faculty of Sport Sciences, Hakim Sabzevari University, Sabzevar, Iran.
3 Full Professor, Department of Exercise Physiology, Faculty of Sport Sciences, Ferdowsi University of Mashhad, Mashhad, Iran.
4 PhD Student in Exercise Physiology, Faculty of Sport Sciences, Hakim Sabzevari University, Sabzevar, Iran.
چکیده [English]
Background and Aim: Physical activity and some antioxidants such as vitamins E and C are effective factors on the immune system. The aim of the present study was to evaluate the effect of four weeks of concurrent training and consumption of vitamins E and C on the acute response of serum immunoglobulin and cortisol to an exhaustive aerobic activity in inactive women. Materials and Methods: The present study was a quasi-experimental study. 24 women were randomly divided into two equal groups (n=12) including concurrent exercise (endurance and resistance) + vitamin supplement (E and C); and concurrent training (endurance and resistance) + placebo groups. Blood sampling was taken before and after a session of exhaustive aerobic activity (activity with an intensity of 75% of the maximum reserve heart rate on the treadmill) and after four weeks of concurrent activity along with supplementation. The concurrent exercise+vitamin supplement (E and C) group performed four weeks of concurrent exercise (three exercise sessions per week) with a 30-day vitamin E and C supplement (500 mg vitamin C and 200 mg vitamin C) was administered twice daily. Serum cortisol and immunoglobulins were measured by gamma and nephelometric methods, respectively. To compare the changes before and after a session of exhausting activity of the two groups, analysis of covariance was used. Moreover, to determine the difference between groups of variables after four stages of measurement, repeated measures analysis of variance and Bonferroni post hoc tests also were used at a significance level of p˂0.05. Results: After the intervention, in the vitamin supplement (E and C) group there was a significant increase in IgM (p=0.03) and IgA (p=0.004). Moreover, there was a significant decrease in IgG (p=0.007) compared to the placebo group. On the other hand, the significant difference in cortisol (p=0.13), upper body muscle strength (p=0.31), lower body muscle strength (p=0.53), upper body muscle endurance (p=0.66), and maximum oxygen consumption (p=0.12) of two concurrent exercise-vitamin supplements (E and C) and concurrent exercise + placebo didn’t observed; while the lower body muscle endurance of the complement group showed significantly increased (p=0.003). Conclusion: consumption of vitamins C and E along with concurrent endurance and resistance training (four weeks) have optimal effects on the safety and physical fitness of inactive women. Vitamins C and E can also improve acute changes in serum immunoglobulins and cortisol levels after debilitating activity.
کلیدواژه‌ها [English]
- Immune system
- Antioxidant vitamins
- Cortisol
- Concurrent exercise
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