نوع مقاله : مقاله پژوهشی
نویسندگان
1 استادیار گروه علوم ورزشی، دانشکده ادبیات و علوم انسانی، دانشگاه زابل، زابل، ایران.
2 استادیار گروه تربیت بدنی و علوم ورزشی، دانشکده ادبیات و علوم انسانی، دانشگاه نیشابور، نیشابور، ایران.
3 استادیار گروه تربیت بدنی و علوم ورزشی، دانشگاه ملی مهارت، تهران، ایران.
4 دکتری فیزیولوژی ورزشی، گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تبریز، ایران.
چکیده
زمینه و هدف: مطالعات نشان داده است که گرملین-1 در اختلال عملکرد بافت چربی در چاقی، دیابت نوع دو و اختلالات متابولیک؛ نقش دارد. هدف از مطالعه حاضر، بررسی تاثیر تمرینات عملکردی با شدت بالا بر سطوح گرملین-1 و مقاومت به انسولین در زنان دارای اضافه وزن و چاق بود. روش تحقیق: در این مطالعه نیمه‌تجربی، 20 زن دارای اضافه وزن و چاق به صورت تصادفی در دو گروه تمرین عملکردی با شدت بالا (10 نفر) و کنترل (10 نفر) تقسیم شدند. آزمودنی‌های گروه تمرینی سه جلسه در هفته به مدت هشت هفته به اجرای تمرینات عملکردی با شدت بالا پرداختند. به منظور اندازه‌گیری گلوکز ناشتا، مقاومت به انسولین و گرملین-1 قبل و پس از مداخله، از آزمودنی‌ها نمونه‌های خونی به عمل آمد. برای تحلیل داده‌ها در نرم افزار SPSS نسخه 16، از آزمون‌های تحلیل کوواریانس و t زوجی در سطح معنی‌داری 05/0>p استفاده شد. یافته ها: بعد از هشت هفته تمرینات عملکردی با شدت بالا، وزن بدن (001/0=p)، شاخص توده بدنی (001/0=p)، درصد چربی (001/0=p)، گلوکز ناشتا (001/0=p)، شاخص مقاومت به انسولین (001/0=p) و غلظت گرملین-1 (03/0=p) ؛ در گروه تجربی نسبت به گروه کنترل به طور معنی‌داری کاهش یافت. نتیجه گیری: نتایج مطالعه حاضر نشان داد تمرینات عملکردی با شدت بالا در زنان دارای اضافه وزن و چاق، منجر به بهبود سطوح گرملین-1 و مقاومت به انسولین می‌گردد؛ بنابراین، از این نوع تمرینات می‌توان به عنوان مداخلات تمرینی کمکی در کنترل و کاهش عوارض مرتبط با اضافه وزن و چاقی استفاده کرد.
کلیدواژه‌ها
عنوان مقاله [English]
The effect of high-intensity functional training on Gremlin-1 levels and insulin resistance in overweight and obese women
نویسندگان [English]
- Javad Nakhzari Khodakheir 1
- Mehdi Zarei 2
- Hamid Reza Zolfi 3
- Amir Shakib 4
1 Assistant Professor at Department of Physical Education and Sport Sciences, School of Human Sciences, University of Zabol, Zabol, Iran.
2 Assistant Professor at Department of Physical Education and Sport Sciences, Faculty of Literature and Humanities, University of Neyshabur, Neyshabur, Iran.
3 Assistant Professor at Department of Physical Education and Sport Science, National University of Skills (NUS), Tehran, Iran.
4 PhD Student in Exercise Physiology, Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran.
چکیده [English]
Background and Aim: Studies have shown that Gremlin-1 can be involved in adipose tissue dysfunction such as obesity, type II diabetes and metabolic disorders. The aim of this study was to investigate the effect of high-intensity functional training on Gremlin-1 levels and insulin resistance in overweight and obese women. Materials and Methods: In this semi-experimental study, 20 overweight and obese women were randomly divided into high-intensity functional training (n=10) and control (n=10) groups. The subjects performed high-intensity functional exercises three times a week during eight weeks. Moreover, blood samples were taken from subjects to measure fasting glucose, insulin resistance, and Gremlin-1 levels before and after the intervention. Data analyzed by SPSS software version 16, based on the covariance and paired t tests at a significance level of p<0.05. Results: After eight weeks of high-intensity functional training, body weight (p=0.001), body mass index (p=0.001), fat percentage (p=0.001), fasting glucose (p=0.001), insulin resistance index (p=0.001) and Gremlin 1 concentration (p=0.03) were significantly reduced in the experimental group compared to control group. Conclusion: The results of the present study showed that high-intensity functional training in overweight and obese women leads to a improve Gremlin-1 levels and insulin resistance; therefore, these types of exercises can be used as exercise interventions in controlling and reducing complications related to overweight and obesity.
کلیدواژه‌ها [English]
- Functional exercise training
- Gremlin-1
- Insulin resistance
- Obesity and overweight
- Women
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