نوع مقاله : مقاله پژوهشی
نویسندگان
1 دانشجوی دکتری فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تبریز، تبریز، ایران.
2 استاد گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تبریز، تبریز، ایران.
3 دانشیار گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تبریز، تبریز، ایران.
چکیده
زمینه و هدف: آسپروسین از بافت چربی ترشح می‌‌شود و نقش اساسی در تنظیم متابولیسم گلوکز و تنظیم اشتها بر عهده دارد و ممکن است یک هدف درمانی برای پیشگیری از بیماری‌‌هایی مانند چاقی، دیابت نوع دو و مقاومت به انسولین باشد. از این‌‌رو، مطالعه حاضر با هدف بررسی تأثیر تمرین تناوبی با شدت بالا (HIIT) بر مقدار سرمی آسپروسین و پروفایل لیپیدی در زنان دارای اضافه وزن و چاقی انجام شد. روش تحقیق: تعداد 30 زن دارای اضافه وزن و چاق ( با 28≤BMI) با دامنه سنی 45-30 سال، در قالب یک طرح مطالعاتی نیمه تجربی با دو مرحله پیش آزمون- پس آزمون، به صورت هدفمند انتخاب شدند و به طور تخصیص تصادفی به دو گروه 15 نفره شامل تمرین تناوبی شدید (HIIT) و کنترل تقسیم گردیدند. دوره آماده‌‌سازی به مدت دو هفته و HIIT به مدت هشت هفته، سه جلسه در هفته با 100 درصد حداکثر ضربان قلب ذخیره به اجرا درآمد. نمونه‌‌های خونی قبل از شروع تمرینات و 48 ساعت بعد از آخرین جلسه تمرینی (بعد از اتمام 10 هفته تمرین) اخذ گردید. مقدار آسپروسین و نیمرخ لیپیدی به ترتیب با روش الایزا و اسپکتروفوتومتری اندازه‌‌گیری شدند. داده‌‌ها با استفاده از آزمون t مستقل و t زوجی و در سطح معنی‌‌داری 05/0>p تجزیه و تحلیل گردیدند. یافته‌‌ها: بعد از 10 هفته مداخله، گروه HIIT کاهش معنی‌‌داری در مقدار آسپروسین (02/0=p)، تری‌‌گلیسرید (01/0=p)، کلسترول تام (01/0=p)، لیپوپروتئین کلسترول با چگالی‌‌کم (01/0=p)، لیپوپروتئین کلسترول با چگالی خیلی‌‌کم (01/0=p)، وزن (0001/0=p)، درصد چربی (0001/0=p) و شاخص توده بدنی (0001/0=p)؛ و افزایش معنی‌‌داری در حداکثر اکسیژن مصرفی (0001/0=p) داشت. با این‌‌حال، تغییر معنی‌‌داری در مقدار لیپوپروتئین کلسترول با چگالی بالا (05/0<p) مشاهده نشد. نتیجه گیری: احتمالا انجام HIIT به عنوان یک روش غیر دارویی و موثر، می‌‌تواند مقدار سرمی آسپروسین و پروفایل لیپیدی را در زنان دارای اضافه وزن و چاق کاهش دهد و ترکیب بدنی آن ها را بهبود بخشد.
کلیدواژه‌ها
عنوان مقاله [English]
The effect of high-intensity interval training on serum Asprosin and lipid profile of overweight and obese women
نویسندگان [English]
- Parvane Dolataabadi 1
- Ramin Amirsasan 2
- Javad Vakili 3
1 PhD Student in Exercise Physiology, Faculty of Physical Education and Sports Sciences, University of Tabriz, Tabriz, Iran.
2 Professor in Department of Exercise Physiology, Faculty of Physical Education and Sports Sciences, University of Tabriz, Tabriz, Iran
3 Associate Professor in Department of Exercise Physiology, Faculty of Physical Education and Sports Sciences, University of Tabriz, Tabriz, Iran.
چکیده [English]
Background and Aim: Asprosin where secreted from adipose tissue plays a key role in regulating glucose metabolism and appetite, and could be a therapeutic target for the prevention of diseases such as obesity, type II diabetes, and insulin resistance. Therefore, the present study aimed to investigate the effect of high-intensity interval training (HIIT) on serum Asprosin and lipid profile in overweight and obese women. Materials and Methods: Thirty overweight and obese women (BMI≥28) with an age range of 30-45 years were purposefully selected in a quasi-experimental research with pre - test to post-test design. They randomly divided into two groups including 15 subjects in every HIIT and control group. The protocol was included preparation period for two weeks, eight weeks for the HIIT, and also they performed three sessions per week with 100% maximum reserve heart rate. Blood samples were taken before and 48 hours after the last training session (following 10 weeks of training). The amount of Asprosin and lipid profile were measured by ELISA and spectrophotometry methods respectively. Data were analyzed using Independent t-test and paired sample t-test at a significant level of p<0.05. Results: After 10 weeks of intervention, HIIT group showed a significant decrease in amount of Asprosin (p=0.02), triglyceride (p=0.01), total cholesterol (p=0.01), low density lipoprotein cholesterol (p=0.01), very low density lipoprotein cholesterol (p=0.01), weight (p=0.0001), fat percentage (p=0.0001) and BMI (p=0.0001), but a significant increase also observed in maximal oxygen consumption (p=0.0001). However, no significant increase in high density lipoprotein cholesterol (p>0.05) was observed. Conclusion: Probably HIIT as a non-pharmacological and effective method can reduce serum Asprosin and lipid profile in overweight and obese women and therefore improve their body composition.
کلیدواژه‌ها [English]
- High Intensity Interval Training
- Obese woman
- Asprosin
- Lipid profile
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