نوع مقاله : مقاله پژوهشی
نویسندگان
1 کارشناس ارشد فیزیولوژی ورزشی، گروه تربیت بدنی، واحد بجنورد، دانشگاه آزاد اسلامی، بجنورد، ایران.
2 استادیار گروه تربیت بدنی، واحد بجنورد، دانشگاه آزاد اسلامی، بجنورد، ایران.
3 دکتری فیزیولوژی ورزشی، دانشگاه کوثر بجنورد، بجنورد، ایران.
چکیده
زمینه و هدف: فیتوئین-آ سایتوکاین مترشحه از کبد است که با بروز بیماریهای مرتبط با چاقی نظیر مقاومت به انسولین و دیابت نوع دو ارتباط دارد. هدف از پژوهش حاضر بررسی اثر تمرین تناوبی شدید بر سطح سرمی فیتوئین-آ، انسولین، گلوکز ناشتا و مقاومت به انسولین در زنان جوان چاق بود. روش تحقیق: تعداد 20 زن چاق بهطور تصادفی به دو گروه تجربی (میانگین سنی 32/5±4/14 سال و شاخص توده بدنی 33/18±6/12 کیلوگرم/مترمربع) و کنترل (میانگین سنی 35/45±2/33 سال و شاخص توده بدنی 31/58±1/65 کیلوگرم/مترمربع) تقسیم شدند. آزمودنیها در گروه تجربی در 8 هفته تمرین تناوبی شدید شامل یک دقیقه تناوب دویدن با شدت 90 درصد حداکثر ضربان قلب با 1 دقیقه تناوب استراحت دویدن با شدت 60-50 درصد حداکثر ضربان قلب، 20 دقیقه در هر جلسه، 3 جلسه در هفته شرکت کردند. اندازهگیری شاخصهای خونی و ترکیب بدنی مورد بررسی، قبل و بعد از اجرای پروتکل تمرینی انجام گرفت. تجزیهوتحلیل دادهها به کمک آزمون تحلیل کوواریانس و آزمون t زوجی در سطح معنی داری <۰/۰5p انجام شد. یافتهها: بر اساس آزمون تحلیل کوواریانس، تغییرات سطوح سرمی فیتوئین- آ (0/04=p)، انسولین (0/03=p)، وزن (001/0=p)، شاخص توده بدنی (005/0=p)، درصد چربی (0/0001=p) و محیط کمر (0/002=p) در گروه تمرین نسبت به گروه کنترل کاهش معنی داری داشت. نتیجه گیری: به نظر میرسد کاهش سطوح فیتوئین-آ پس از تمرینات تناوبی شدید، در بهبود مقاومت به انسولین در زنان جوان چاق نقش ندارد.
کلیدواژهها
عنوان مقاله [English]
Changes in serum levels of Fetuin-A and insulin resistance following high intensity interval training in young obese women
نویسندگان [English]
- Somayeh Saeedi 1
- Najmeh Rezaeian 2
- Maryam Karimi 3
1 MSc in Exercise Physiology, Department of Physical Education, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran.
2 Assistant Professor, Department of Physical Education, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran.
3 PhD of Exercise Physiology, Kosar University of Bojnord, Bojnord, Iran.
چکیده [English]
Background and Aim: Fetuin-A is a liver-secreted cytokine that has been linked to a number of diseases correlated to obesity and its related metabolic diseases such as insulin resistance and type II diabetes. The purpose of this study was to investigate effects of high intensity interval training (HIIT) on serum levels of Fetuin-A, insulin, fasting glucose, and insulin resistance in young obese women. Materials and Methods: Twenty obese women randomly divided into two groups including experimental (mean age 32.5±4.14 years, and body mass index 33.18±6.12 Kg/m2) and control (mean age 35.45±2.33 years, and body mass index 31.58±1.65 Kg/m2) groups. Subjects in experimental group participated in the eight weeks of HIIT including one minute of running interval up to 90-95 percent of maximal heart rate and 1-3 minutes of rest interval up to 50-60 percent of maximal heart rate, 20 minutes per session, and three sessions per week. Blood factors and body composition indices were assessed before and after training protocol. Statistical analysis was done by the covariance and paired t-test at the significant level of p < 0.05. Results: Based on the covariance analysis, the changes in serum levels of Fetuin-A (p=0.04), insulin (p=0.03), weight (p=0.001), body mass index (p=0.005), body fat percent (p=0.0001), and waist circumference (p=0.002) were significantly decreased after HIIT compared to control group. Conclusion: It seems that decreased level of Fetuin-A following HIIT do not play a role in improving insulin resistance in young sedentary obese women.
کلیدواژهها [English]
- High intensity interval training
- Fetuin-A
- Insulin resistance
- Obesity
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