نوع مقاله : مقاله پژوهشی
نویسندگان
1 دانشجوی دکتری فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تبریز، تبریز، ایران.
2 استاد گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تبریز، تبریز، ایران.
3 دانشیار گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تبریز، تبریز، ایران.
4 استاد گروه فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه عراق، کربلا، عراق.
چکیده
کلیدواژهها
عنوان مقاله [English]
نویسندگان [English]
Background and Aim: Agouti-related protein (AgRP) is a signaling peptide that influences feeding behavior, energy homeostasis, and fat accumulation. Recent studies suggest that high-intensity interval training (HIIT) may impact AgRP levels, however, current results are inclusiveand contradictory. Therefore, the aim of this study was to investigate the effect of eight weeks of HIIT on AgRP levels, lipid profile and anthropometric indices in overweight and obese men. Materials and Methods: In a semi-experimental study, 32 overweight and obese male volunteers with a body mass index (BMI) of 25–35 and aged 30 to 35 years were randomly assigned to either a high-intensity interval training (HIIT) group (n = 16) or a control group (n = 16). The intervention included a two-week familiarization period followed by eight weeks of HIIT, during which participants trained three sessions per week at an intensity of 100–140% of their maximal oxygen uptake speed (vVO₂max). Blood samples were collected 48 hours before and after the exercise protocol in a fasted state, and data were evaluated using ANCOVA at a significance level of p ≤ 0.05. Findings: After eight weeks of intervention, a significant increase in serum AgRP level (p = 0.0001) and decrease in the waist-to-hip ratio, triglyceries (p = 0.0001), total cholesterol (p = 0.0001), low-density lipoprotein (p = 0.0001), and very-low-density lipoprotein (p = 0.0001) were observed in the HIIT group compared to the control group, while high-density lipoprotein reduced significantly only in the control group (p = 0.0001). Conclusion: Based on the results, HIIT may increase serum AgRP levels, improve the lipid profile, and reduce waist-to-hip ratio in overweight and obese men; thus, it can serve as an effective exercise strategy for appetite regulation and the improvement of anthropometric and lipid indices.
کلیدواژهها [English]
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