تأثیر مصرف هشت هفته مکمل قرص انار بر شاخص‌های التهابی و آسیب عضلانی در مردان دارای اضافه‌وزن غیر ورزشکار تحت تاثیر شدت‌های مختلف VO2max

نوع مقاله: مقاله پژوهشی

نویسندگان

1 استادیار، گروه علوم ورزشی، دانشکده علوم انسانی، دانشگاه آزاد اسلامی واحد اهر، اهر، ایران

2 دانشجوی دکتری، گروه علوم ورزشی، دانشکده علوم تربیتی و روان شناسی، دانشگاه محقق اردبیلی، اردبیل، ایران.

3 مربی، گروه علوم ورزشی، دانشکده علوم انسانی، دانشگاه آزاد اسلامی واحد جلفا، جلفا، ایران.

چکیده

زمینه و هدف: با توجه به اهمیت مصرف آنتی اکسیدان‌های گیاهی در جلوگیری از شاخص­های التهابی و آسیب عضلانی، هدف از مطالعه حاضر بررسی تأثیر مصرف هشت هفته مکمل انار بر شاخص‌های التهابی و آسیب عضلانی در مردان دارای اضافه‌وزن غیر ورزشکار بود. روش تحقیق: 20 مرد سالم در یک طرح نیمه تجربی - دوسوکور، به‌صورت تصادفی در دو گروه مکمل انار (10=n) و دارونما (10=n) به مدت هشت هفته، سه جلسه در هفته با شدت 50 تا 80 درصد حداکثر اکسیژن مصرفی (VO2max) دویدند؛ بعد از هشت هفته، تمامی آزمودنی­ها در آزمون­های ورزشی 60 و 75 (VO2max) شرکت کردند. نمونه‌ خون وریدی در مرحله پایه، بلافاصله بعد و 24 ساعت پس از شدت‌های مختلف فعالیت هوازی، برای اندازه­ گیری شاخص ­های التهابی و آسیب عضلانی گرفته شد. از آزمون آماری t همبسته و تحلیل واریانس با اندازه‌گیری مکرر با آزمون تعقیبی بونفرونی استفاده شد. یافته‌ها: میزان عامل نکروز دهنده تومور آلفا (TNF-α) و پروتئین واکنش‌گرC  (CRP) در هر دو شدت، بلافاصله پس از فعالیت ورزشی در هر دو گروه مکمل انار و دارونما افزایش معنی‌دار داشت (0/001=p) و میزان  TNF-α 24 ساعت پس از فعالیت ورزشی در گروه مکمل و دارونما با هر دو شدت 60 و 75 درصد (VO2max) به ترتیب کاهش معنی‌داری داشت (0/001=p) (p=0/001)، (­p=0/01) (p=0/01). و بین گروه‌ها تفاوت معنی‌داری یافت نشد (0/07=P)، ولی شاخص CRP 24 ساعت پس از فعالیت در گروه مکمل در مقایسه با دارونما بویژه، در 75 درصد شدت، کاهش معنی‌داری داشت (0/3=p). با این حال تغییرات کراتین کیناز (CK) در هیچ‌کدام از گروه‌ها در مراحل متفاوت با شدت‌های مختلف 60 و 75 درصد معنی‌دار نبود. نتیجه گیری: مصرف مکمل انار طی هشت هفته فعالیت ورزشی، در کنترل و کاهش شاخص‌های التهابی بویژه CRP در افراد سالم موثر نشان داد. با این ‌وجود با توجه به مطالعات اندک در این زمینه، انجام مطالعات بیشتر، ضروری به­ نظر می­رسد.

کلیدواژه‌ها


عنوان مقاله [English]

The effect of 8 week of pomegranate supplementation on inflammatory and muscular damage indices in over weight untrained men due todifferent intensity VO2max

نویسندگان [English]

  • Hasan Farhadi 1
  • Soheila Rahimi Fardin 2
  • Behrouz Baghaiee 3
1 Assistant Professor in Sport Sciences, Ahar Branch, Islamic Azad University, Ahar, Iran.
2 PhD student in Sport Sciences, Department of Sport Sciences, Mohaghegh Ardabil University, Ardabil, Iran.
3 Lectureship in Sport Sciences, Julpha Branch, Islamic Azad University, Julpha, Iran.
چکیده [English]

Background and Aim: Considering the importance of the use of plant antioxidants in preventing inflammatory and muscular damage indices, the present study was performed to determine the effect of 8 weeks of pomegranate supplementation and aerobic training on inflammatory and muscular damage indices in overweight men. Materials and Methods: Twenty overweight men were assigned into two equal supplement and placebo groups  as randomized and double-blind study (225mg/day pomegranate or dextrose for 8 week). Meanwhile, both groups participated in running tests with 50 to 80% maximum oxygen consumption (VO2max) 8weeks, 3 sessions/ week. Then, blood samples were taken during three phases at baseline, immediately and 24 hours after different intensities of aerobic exercise (60% and 75% VO2max). The data was analyzed by SPSS software (V: 20) using repeated measure ANOVA and paired T tests at the significant level P≤0.05. Results: The result showed a significant increase in Tumor necrosis factor-alpha and C - reactive protein immediately after the exercise in both groups (P=0.001). However, these indices were decreased 24 hours after exercise in both groups, and this decrement was higher in the pomegranate group (P=0.001), (P=0.01). Although, no significant difference was found in Creatine kinase in any stage of the study in both groups (P=0.27), (P=0.20), but, a significant decrease was found in CRP levels in the supplement group as compared with placebo in 75% VO2max (P=0.03). Conclusion: The results indicated that the combination of regular exercise and pomegranate supplementation had a significant effect on the control and decline of inflammatory markers particularly CRP in overweight males. However, more research is needed based on a few studies conducted in this area.

کلیدواژه‌ها [English]

  • Pomegranate supplementation
  • inflammatory markers
  • muscular damage
  • VO2max

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