عنوان مقاله [English]
Background and Aim: Considering the importance of the use of plant antioxidants in preventing inflammatory and muscular damage indices, the present study was performed to determine the effect of 8 weeks of pomegranate supplementation and aerobic training on inflammatory and muscular damage indices in overweight men. Materials and Methods: Twenty overweight men were assigned into two equal supplement and placebo groups as randomized and double-blind study (225mg/day pomegranate or dextrose for 8 week). Meanwhile, both groups participated in running tests with 50 to 80% maximum oxygen consumption (VO2max) 8weeks, 3 sessions/ week. Then, blood samples were taken during three phases at baseline, immediately and 24 hours after different intensities of aerobic exercise (60% and 75% VO2max). The data was analyzed by SPSS software (V: 20) using repeated measure ANOVA and paired T tests at the significant level P≤0.05. Results: The result showed a significant increase in Tumor necrosis factor-alpha and C - reactive protein immediately after the exercise in both groups (P=0.001). However, these indices were decreased 24 hours after exercise in both groups, and this decrement was higher in the pomegranate group (P=0.001), (P=0.01). Although, no significant difference was found in Creatine kinase in any stage of the study in both groups (P=0.27), (P=0.20), but, a significant decrease was found in CRP levels in the supplement group as compared with placebo in 75% VO2max (P=0.03). Conclusion: The results indicated that the combination of regular exercise and pomegranate supplementation had a significant effect on the control and decline of inflammatory markers particularly CRP in overweight males. However, more research is needed based on a few studies conducted in this area.
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