عنوان مقاله [English]
نویسندگان [English]چکیده [English]
Background and Aim: Apoptosis is extremely important to regulate the immune system, particularly lymphocytes or reduce the risk of starting a devastating response؛ therefore; the purpose of this study was to investigate the effects of exhaustive exercise after eight-week resistance exercise on lymphocyte apoptosis in inactive women. Materials and Methods: 24 healthy inactive women were randomly divided into experimental and control groups with average 21.7 ± 0.9 and 20.58 ±0.9 ages respectively. The experimental group completed eight-week resistance training. Moreover, one exhaustive exercise session was performed for both groups. Blood samples were collected immediately before and after training period, after exhaustiveexercise, and 24 hours later. Statistical analyzing between groups was analyzed by one-way ANOVA, and changes within groups were measured by ANOVA with repeated measures (p>0.05). Results: Significant differences were observed between two groups in lymphocytes apoptosis. Apoptosis increased significantly after an exhaustive exercise in control group (p=0.001), and also, after 24 hours of activity was still high (p=0.496). Lymphocyte apoptosis was significantly differed after eight-week of practice in experimental group (p=0.000). However, these changes were not significant after one session of exhausting exercise, After 24 hours of activity, and it lead to apoptosis decrease significantly in experimental group, although, control group was not showed a significant reduction (p=0.020). Conclusion: resistance training had positive effect on the ability of immune system in order to face intensive exercise. It is possible that resistance exercise may have beneficial effect on cell apoptosis and it could improve public health.
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