پاسخ شاخص های التهابی و آسیب عضلانی به فعالیت شدید هوازی در پسران سالم: ارتباط بین شاخص ها

نوع مقاله: مقاله پژوهشی

نویسندگان

1 دانشیار فیزیولوژی ورزشی/ دانشکده علوم ورزشی/ دانشگاه علامه طباطبائی/ تهران

2 دانشجوی دکتری فیزیولوژی ورزشی/ گروه تربیت بدنی و علوم ورزشی/ دانشگاه محقق اردبیلی/ اردبیل

چکیده

زمینه و هدف: با توجه به نتایج محدود و متناقض مربوط به پاسخ‌ شاخص‌های التهابی و آسیب عضلانی به فعالیت ورزشی شدید در نوجوانان، هدف از تحقیق حاضر بررسی پاسخ و رابطه بین برخی شاخص ­های التهابی و شاخص آسیب عضلانی در پسران 14 تا 16 سال در پاسخ به فعالیت ورزشی شدید بود. روش­ تحقیق: 24 پسر سالم 14 تا 16 سال در دو گروه تمرین (12 نفر) و کنترل (12 نفر) داوطلب شرکت در پژوهش شدند. آزمودنی­ های گروه تمرین، آزمون ورزشی فزاینده بالک را بر اساس پروتکل تعریف شده انجام دادند. جهت بررسی سطوح فیبرینوژن پلاسما، پروتئین واکنشیC و کراتین کیناز سرم از گروه تمرین در حالت پایه و 2 دقیقه بعد از اتمام آزمون ورزشی و از گروه کنترل در حالت پایه و 48 ساعت بعد از آن خونگیری به عمل آمد. جهت بررسی شاخص­ های مورد نظر از روش­های آماری t زوجی و t مستقل و نیز ضریب همبستگی پیرسون و ضریب بتا در سطح معنی­ داری 0/05>p استفاده شد. یافته ها: مقادیر فیبرینوژن پلاسما (0/01=p)، پروتئین واکنشی (0/01=p) و کراتین کیناز سرم (0/01=p) بلافاصله پس از فعالیت بدنی فراینده افزایش معنی­ داری یافتند. در بررسی ارتباط متغیرها، بین فیبرینوژن پلاسما با پروتئین واکنشیC سرم (0/675=p=0/016، r) و فیبرینوژن پلاسما با کراتین کیناز سرم (0/61=p=0/01، r) در گروه تمرین همبستگی معنی ­دار مثبت یافت شد.  نتیجه­ گیری: بر اساس نتایج حاصل از این مطالعه در نوجوانان شاخص­های التهابی فیبرینوژن پلاسما و پروتئین واکنشیC سرم و شاخص آسیب عضلانی کراتین کیناز تحت تاثیر فعالیت ورزشی شدید هوازی افزایش می­یابد که نشانگر وجود التهاب و آسیب عضلانی در پاسخ به فعالیت شدید می­باشد.  

کلیدواژه‌ها


عنوان مقاله [English]

Inflammatory markers and muscle damage indices response to intense exercise in healthy boys: relationship between the markers

نویسندگان [English]

  • Bakhtyar Tartibian 1
  • Bahman Ebrahimi Torkamani 2
چکیده [English]

Background and Aim: Based on the limited and inconsistent results in regarding to the effects of intense exercise on inflammatory markers and muscle damage in adolescents, the aim of this study was to examine the response and relationship between some inflammatory markers and muscle damage in 14-16 years old boys in response to incremental physical activity. Materials and Methods: Twenty-four healthy 14-16 years old boys volunteered and divided in two groups as exercise (n=12) and control (n=12) groups. The exercise group performed incremental modified Balke protocol physical activity, according to the defined protocol. In order to examine the levels of plasma fibrinogen, Serum CRP and CPK blood samples were collected in baseline and immediately 2 minutes after incremental physical activity in trained group and also in baseline and 48 hours later in the controls group. To statistical analysis the dependent t-test, independent t-test, Pearson's correlation coefficient and beta coefficient  were used and the significant level set at pResults: Serum CRP (p=0.01), CPK (p=0.01) and plasma fibrinogen (p=0.01) levels significantly increased immediately after intense exercise in the exercise group (p<0.01). Moreover, the relationship between variables showed, significant correlation between plasma fibrinogen with Serum CRP (r=0.661 p<0.016) and plasma fibrinogen with Serum CPK (r=0.617, p< 0.011) in the exercise group. Conclusions: According to results of this study the inflammatory markers and muscle damage  indices were affected by intense aerobic exercise in adolescents, which indicates the presence of inflammation and muscle damage in response to intense aerobic exercise. 

کلیدواژه‌ها [English]

  • inflammatory markers
  • Muscle damage
  • Modified balke protocol
  • Boys

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