پایش آثار درازمدت مصرف استروئیدهای آنابولیک-آندروژنیک روی برخی از شاخص های قلبی- عروقی اندام پروران پیشکسوت

نوع مقاله: مقاله پژوهشی

نویسندگان

1 دانشجوی دکتری فیزیولوژی ورزش، پردیس بین المللی کیش، دانشگاه تهران،کیش، ایران

2 استاد فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تهران، تهران، ایران

3 دانشیار فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه تهران ،تهران، ایران

4 استاد فیزیولوژی ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه مازندران، بابلسر، ایران

چکیده

زمینه و هدف: بسیاری از مطالعات گذشته آثار کوتاه مدت مواد ممنوعه نیروزا را تائید کردند، با این حال آثار درازمدت مصرف این مواد بر دستگاه­های مختلف بدن، به ویژه دستگاه قلبی عروقی نامشخص است. هدف پژوهش حاضر، مطالعه آثار دراز مدت قلبی عروقی ناشی از استروئیدهای آنابولیک -آندروژنیک در مصرف­­کنندگان پیشکسوت درگیر در ورزش­های قدرتی بود. روش تحقیق: 23 شرکت­کننده مرد به سه گروه اندام­پرور پیشکسوت (8 نفر)، اندام­ پرور جوان در حال مصرف استروئیدهای آنابولیک -آندروژنیک (8 نفر) و کنترل (7 نفر) تقسیم شدند. ترکیب بدنی شرکت­کنندگان و نیز پاسخ­ شاخص­های همودینامیکی مرتبط با استرس قلبی- عروقی از قبیل فشار خون سیستولی و دیاستولی، حاصل­ضرب دوگانه، میانگین فشار سرخرگی و ضربان قلب، قبل و پس از فعالیت ورزشی درمانده­ساز روی تردمیل اندازه­گیری شد. یافته ­ها: روش تحلیل واریانس یک سویه در تغییرات شاخص­های مورد نظر پس از فعالیت نسبت به قبل، بین گروه پیشکسوت و گروه کنترل تفاوت معنی ­داری نشان نداد (0/05<p). با وجود این، ضربان قلب (0/001=p)، فشارخون دیاستولی (پیشکسوت- جوان، 0/002=p؛ کنترل- جوان، 0/01=p) و حاصل­ضرب دوگانه (کنترل- جوان، 0/05=p؛ پیشکسوت- جوان،  0/04=p) پس از فعالیت نسبت به قبل آن، به­طور معنداری در گروه جوان در حال مصرف بالاتر از گروه پیشکسوت و کنترل بود. نتیجه ­گیری: نتایج مطالعه حاضر موید برگشت­پذیر بودن عملکرد همودینامیکی قلب و عروق متعاقب قطع مصرف بلند مدت مواد استروئیدهای آنابولیک اندروژنیک می­باشد؛ هر چند مطالعه بیشتر برای تائید این یافته ها ضروری است.

کلیدواژه‌ها


عنوان مقاله [English]

The monitoring of prolonged effects of anabolic - androgenic steroid on cardiovascular indices in former bodybuilders

نویسندگان [English]

  • Hoda Abdi Hamzekolai 1
  • Abbas Ali Gaeini 2
  • Mohammad Reza Kordi 3
  • Valiolah Dabidi Roshan 4
1 Ph.D Student of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tehran, International Campus-Kish Island, Kish, Iran
2 Professor of Exercise Physiology, Department of Physical Education and Sport Sciences, University of Tehran, Tehran,Iran
3 Associate Professor, Department of Physical Education and Sport Sciences, University of Tehran, Tehran, Iran.
4 Professor of Exercise Physiology, Department of Physical Education and Sport Sciences, University of Mazandaran, Babolsar, Iran
چکیده [English]

Background and Aim: There are many studies about the acute effects of anabolic androgenic steroids on the
cardiovascular system, however, there is little information on its prolonged effects. The purpose of this study was to
evaluate the long-term effects of anabolic - androgenic steroids on cardiovascular indices in the former bodybuilders.
Materials and Methods: Twenty-three male people were divided into 3 groups: former bodybuilders (n=8), young
current anabolic anderogenic steroid (AAS) users bodybuilders (n=8) and control (n=7) groups. Body composition,
hemodynamic cardiovascular stress responses such as systolic and diastolic blood pressure, double product, mean
arterial pressure and heart rate was evaluated prior and after an exhaustive test on a treadmill. Results: The one way
ANOVA showed no significantly changes between former bodybuilders and control groups before and after exercise
(p>0.05). But heart rate (p=0.001), diastolic blood pressure (formers-young, p=0.002 and young-control, p=0.01) and
double product (young-control, p=0.05 and formers-young, p=0.04) were significantly higher in young current users
group as compare to other groups. Conclusion: The results of this study confirmed the reversibility of cardiovascular
hemodynamic performance after discontinuation of long-term of using of anabolic androgenic steroids, although more
study is needed to confirm these findings.

کلیدواژه‌ها [English]

  • Anabolic androgenic steroid
  • Cardiovascular risk factor
  • Formers body builders athletes
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