تاثیر 8 هفته تمرین مقاومتی و مکمل یاری دارچین بر سطوح پلاسمایی لپتین و آدیپونکتین در زنان غیر فعال دارای اضافه وزن

نوع مقاله: مقاله پژوهشی

نویسندگان

1 کارشناس ارشد فیزیولوژی ورزشی، گروه علوم ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه رازی، کرمانشاه، ایران.

2 دانشیار، گروه علوم ورزشی، دانشکده تربیت بدنی و علوم ورزشی، دانشگاه رازی، کرمانشاه، ایران.

10.22077/jpsbs.2019.2082.1465

چکیده

زمینه و هدف: چاقی با بسیاری از مشکلات سلامتی از جمله دیابت، فشارخون، بیماری‌های شریان کرونری و استئوآرتریت مرتبط است. هدف این تحقیق بررسی اثر مکمل‌سازی تمرین مقاومتی با دارچین بر سطح لپتین و آدیپونکیتن در زنان دارای اضافه وزن بود. روش تحقیق: چهل زن دارای اضافه وزن در چهار گروه 10 نفری شامل گروه تمرین مقاومتی+مصرف دارچین، گروه تمرین مقاومتی، گروه مکمل دارچین و گروه کنترل قرار گرفتند. سپس گروه‌های تجربی به مدت 8 هفته، 3 جلسه در هفته به اجرای تمرین مقاومتی با شدت 60 تا 80 درصد یک تکرار بیشینه پرداختند. آزمودنی‌ها در گروه تمرین و مکمل در سه وعده اصلی غذایی روزانه، مقدار 7 میلی‌گرم پودر دارچین (به صورت کپسول) به ازای هر کیلوگرم از وزن بدن خود دریافت کردند. نمونه خونی قبل از اجرای پروتکل و 48 ساعت پس از آخرین جلسه تمرین به منظور اندازه گیری میزان لپتین و آدیپونکتین پلاسمای گرفته شد. به منظور استخراج نتایج از آزمون t زوجی و آزمون کوواریانس در سطح معنی داری 0/05p≤ استفاده گردید. یافته ها: در گروه های تمرین مقاومتی+ مصرف دارچین (به ترتیب با 0/001>p و 0/01>p)، تمرین مقاومتی (0/01>p) و مکمل دارچین (به ترتیب با 0/01>p و 0/02>p) به طـور معنـی‌داری میزان لپتین کاهش و میزان آدیپونکتین افزایش یافت. هر چند، بین تاثیرتمرین مقاومتی و مکمل دارچین بر لپتین (0/07>p) و آدیپونکتین (0/24>p) تفاوت معنی دار مشاهده نگردید؛ اما تمرین مقاومتی + مصرف دارچین در مقایسه با تمرین مقاومتی و مصرف مکمل دارچین به تنهایی، موجب کاهش بیشتر لپتین (0/01>p) و افزایش بیشتر آدیپونکتین (0/01>p) گردید. نتیجه گیری: تمرینات منظم مقاومتی همزمان با مصرف مکمل دارچین، به واسطه بهبود مقادیر لپتین و آدیپونکتین خطر بالقوه ابتلا به بیماری‌های قلبی- عروقی را کاهش می‌دهد و می‌توان از آن به عنوان درمان غیردارویی مؤثر به منظور پیشگیری از این بیماری‌ها استفاده نمود.

کلیدواژه‌ها


عنوان مقاله [English]

Effect of 8 weeks of resistance training and supplementation of cinnamon on plasma levels of leptin and adiponectin in overweight women

نویسندگان [English]

  • Shokofeh Maleki 1
  • Naser Behpoor 2
  • Vahid Tadibi 2
1 MSc in Exercise Physiology, Department of Sport Sciences, Faculty of Physical Education and Sport Sciences, Razi University, Kermanshah, Iran.
2 Associate Professor, Department of Sport Sciences, Faculty of Physical Education and Sport Sciences, Razi University, Kermanshah, Iran.
چکیده [English]

Background and Aim: Obesity is associated with many health problems, including diabetes, hypertension, coronary artery disease, and osteoarthritis. The purpose of this study was to investigate the effect of cinnamon supplementation with resistance training on plasma levels of leptin, adiponectin in overweight women. Materials and Methods: Forty overweight women were divided into 4 groups (n=10) including resistance training +cinnamon supplementation, resistance training, cinnamon supplementation and control groups. Experimental group performed resistance exercises for 8 weeks, 3 sessions per week up to 60-80 percent of one repetition maximum. The subjects in the resistance training +cinnamon supplementation and cinnamon supplementation groups, received 7 mg of cinnamon powder per kg of body weight three times a day. Blood samples as serum leptin and adiponectin levels were taken before and also 48 hours after the last exercise session of the protocol. For statistical analysis, the paired t-test and covariance test were used to examine the difference between groups at the significant level of p≤0.05. Results: The result indicated significant decreases in leptin levels and increases of the adiponectin level in resistance training groups + cinnamon intake (p < 0.001 and p < 0.01 respectively), resistance training group (p < 0.01) and cinnamon supplement (p < 0.01 and p < 0.02 respectively). Moreover, there was no significant differences between the effect of cinnamon supplementation on leptin (p < 0.07) and adiponectin (p < 0.24); but resistance training + cinnamon supplementation showed higher decreasing in leptin (p < 0.01) and more increasing in adiponectin levels (p < 0.01) compared to resistance training and cinnamon supplementation alone. Conclusion: Regular resistance training along with supplementation of cinnamon can reduces the risk of cardiovascular disease by improving the levels of leptin and adiponectin and it can be used as an effective non-pharmacological treatment to prevent these diseases.

کلیدواژه‌ها [English]

  • resistance training
  • Cinnamon supplement
  • Adipocytokines
  • Body fat
Ahmadi, R., Omidali, F., & Pishghadam, F. (2017). Effect of hydro alcoholic Cinnamomum zeylanicum extract on leptine, triglyceride, total cholestrol levels and body weight in Male Wistar rats exposed to air pollution. Journal of Animal Sciences, 30(1). 15-24. [Persian]

Anderson, R. A., Broadhurst, C. L., Polansky, M. M., Schmidt, W. F., Khan, A., Flanagan, V. P., ... & Graves, D. J. (2004). Isolation and characterization of polyphenol type-A polymers from cinnamon with insulin-like biological activity. Journal of Agricultural and Food Chemistry, 52(1), 65-70.

Bahram, M., & Mogharenesi, M. (2014). The effect of twelve weeks high intensity interval training (HIIT) on leptin levels and obesity dependent factors among female students suffering overweight. Journal of Biological Sciences, 6(4), 451-465. [Persian]

Balasasirekha, R., & Lakshmi, U. K. (2011). Effect of cinnamon and garlic on hyperlipidemics. International Journal of Nutrition and Metabolism, 3(7), 77-89.

Boqué, N., Campión, J., de la Iglesia, R., de la Garza, A. L., Milagro, F. I., San Román, B., ... & Martínez, J. A. (2013). Screening of polyphenolic plant extracts for anti‐obesity properties in Wistar rats. Journal of the Science of Food and Agriculture, 93(5), 1226-1232.

Brooks, N., Layne, J. E., Gordon, P. L., Roubenoff, R., Nelson, M. E., & Castaneda-Sceppa, C. (2007). Strength training improves muscle quality and insulin sensitivity in Hispanic older adults with type 2 diabetes. International Journal of Medical Sciences, 4(1), 19-27.

Fu, Y., Luo, N., Klein, R. L., & Garvey, W. T. (2005). Adiponectin promotes adipocyte differentiation, insulin sensitivity, and lipid accumulation. Journal of Lipid Research,, 46(7), 1369-79.

Hara, T., Fujiwara, H., Nakao, H., Mimura, T., Yoshikawa, T., & Fujimoto, S. (2005). Body composition is related to increase in plasma adiponectin levels rather than training in young obese men. European Journal of Applied Physiology, 94(5-6), 520-526.

Gheibi, N., Parvizi, M. R., & Jahani Hashemi, H. (2005). The effect of cinnamon on glucose concentration of diabetic rats in presence or absence of insulin. Journal of Qazvin University of Medical Sciences, 9(3), 3-7. [Persian]

Kelly, A. S., Steinberger, J., Olson, T. P., & Dengel, D. R. (2007). In the absence of weight loss, exercise training does not improve adipokines or oxidative stress in overweight children. Metabolism, 56(7), 1005-1009.

Klimcakova, E., Polak, J., Moro, C., Hejnova, J., Majercik, M., Viguerie, N., ... & Stich, V. (2006). Dynamic strength training improves insulin sensitivity without altering plasma levels and gene expression of adipokines in subcutaneous adipose tissue in obese men. The Journal of Clinical Endocrinology & Metabolism, 91(12), 5107-5112.

Masamoto, Y., Kawabata, F., & Fushiki, T. (2009). Intragastric administration of TRPV1, TRPV3, TRPM8, and TRPA1 agonists modulates autonomic thermoregulation in different manners in mice. Bioscience, Biotechnology and Biochemistry, 73(5), 80796-1–7

Martins, C., Robertson, M. D., & Morgan, L. M. (2008). Effects of exercise and restrained eating behavior on appetite control. Proceedings of the Nutrition Society , 67(1), 28-41.

Mir, E., Attarzadeh Hosseini, S. R., Hejazi, K., & Mir Sayeedi, M. (2016). Effect of eight weeks of endurance and resistance training on serum adiponectin and Insulin resistance index of inactive elderly men. Journal of Gorgan University Medical Sciences, 18(1), 69-77. [Persian]

Modaresi, M. (2011). The effect of cinnamon extract on serum proteins levels of male Balb/c mice. Armaghane Danesh, 16(5), 444-452. [Persian]

Naghavi Moghadam, A. A., & Shiravand, M. (2016). Effect of 8 weeks of resistance training with cinnamon supplementation in obese men glycemic index. Journal of Nurse and Physician Wthin War, 4(12), 133-139. [Persian]

Otsuka, R., Yatsuya, H., Tamakoshi, K., Matsushita, K., Wada, K., & Toyoshima, H. (2006). Perceived psychological stress and serum leptin concentrations in Japanese men. Obesity, 14(10), 1832-1838.

Peng, X., Cheng, K. W., Ma, J., Chen, B., Ho, C. T., Lo, C., ... & Wang, M. (2008). Cinnamon bark proanthocyanidins as reactive carbonyl scavengers to prevent the formation of advanced glycation endproducts. Journal of Agricultural and Food Chemistry, 56(6), 1907-1911.

Plinta, R., Olszanecka-Glinianowicz, M., Drosdzol-Cop, A., Chudek, J., & Skrzypulec-Plinta, V. (2011). The effect of three-month pre-season preparatory period and short-term exercise on plasma leptin, adiponectin, visfatin, and ghrelin levels in young female handball and basketball players. Journal of Endocrinological Investigation, 35(6), 595-601.

Qin, B., Panickar, K. S., & Anderson, R. A. (2010). Cinnamon: potential role in the prevention of insulin resistance, metabolic syndrome, and type 2 diabetes. Journal of Diabetes Science and Technology, 4(3), 685-693.

Schulze, M. B., Shai, I., Rimm, E. B., Li, T., Rifai, N., & Hu, F. B. (2005). Adiponectin and future coronary heart disease events among men with type 2 diabetes. Diabetes, 54(2), 534-539.

Shahidi, F., & Pirhadi, S. (2011). The effect of physical exercise and training on serum leptin levels. Razi Journal of Medical Sciences, 21(126), 1-14. [Persian]

Souri, R., Hasani Ranjbar, S. H., Vahabi, K., & Shabkhiz, F. (2011). The effect of aerobic exercise on serum RBP4 and insulin resistance index in type 2 diabetic patients. Iranian Journal of Diabetes and Lipid, 10(4), 388-97. [Persian]

Trapp, E. G., Chisholm, D. J., Freund, J., & Boutcher, S. H. (2008). The effects of high-intensity intermittent exercise training on fat loss and fasting insulin levels of young women. International Journal of Obesity, 32(4), 684-691.

Yang, W. S., Lee, W. J., Funahashi, T., Tanaka, S., Matsuzawa, Y., Chao, C. L., ... & Chuang, L. M. (2001). Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. The Journal of Clinical Endocrinology & Metabolism, 86(8), 3815-3819.

Yang, W. S., Lee, W. J., Funahashi, T., Tanaka, S., Matsuzawa, Y., Chao, C. L., ... & Chuang, L. M. (2002). Plasma adiponectin levels in overweight and obese Asians. Obesity Research, 10(11), 1104-1110.

Yatagai, T., Nishida, Y., Nagasaka, S., Nakamura, T., Tokuyama, K., Shindo, M., … & Ishibashi, S. (2003). Relationship between exercise training-induced increase in insulin sensitivity and adiponectinemia in healthy men. Endocrine Journal, 50(2), 233-8.

Zahmatkesh, M., Fallah Huseini, H., Hajiaghaee, R., Heidari, M., Mehrafarin, A., Tavakoli-far, B. (2012). The effects of cinnamomum zeylanicum J. Presl on blood glucose level in patients with type 2 diabetes, a doubleblind clinical trial. Journal of Medicinal Plants, 11(41), 258-263. [Persian]