اثر مکمل دهی ترکیبی کراتین، گلوتامین و تورین بر پاسخ شاخص های آسیب عضلانی و کبدی ناشی از فعالیت ورزشی تناوبی شدید در مردان تمرین کرده

نوع مقاله: مقاله پژوهشی

نویسندگان

1 کارشناس ارشد فیزیولوژی ورزشی کاربردی، دانشکده علوم ورزشی، دانشگاه گیلان، رشت، ایران.

2 استاد گروه فیزیولوژی ورزشی، دانشکده علوم ورزشی، دانشگاه گیلان، رشت، ایران.

چکیده

زمینه و هدف: مکمل ورزشی CGT ترکیبی از سه ماده ی کراتین، گلوتامین و تورین می باشد که به ترتیب 50، 30 و 20 درصد محتوای کل مکمل را تشکیل می دهند. هدف از پژوهش حاضر بررسی اثر مکمل دهی ترکیبی کراتین، گلوتامین و تورین بر پاسخ شاخص های آسیب عضلانی و کبدی ناشی از فعالیت ورزشی تناوبی شدید در مردان تمرین کرده بود. روش تحقیق: 19 نفر مرد تمرین کرده (سن 73/0±28/22 سال، نمایه توده بدن 66/1±35/22 کیلوگرم بر متر مربع و درصد چربی بدن 93/2±87/8) به صورت تصادفی به دو گروه مصرف مکمل (9 نفر) و دارونما (10 نفر) تقسیم شدند. گروه مکمل به مدت 2 هفته مکمل CGT را به مقدار 12 گرم در روز و گروه دارونما به همان میزان پودر نشاسته مصرف کرد. هر 2 گروه در مرحله قبل و بعد از مکمل گیری پروتکل فعالیت ورزشی تناوبی شدید (HIIE) را انجام دادند. نمونه‌های خونی در 6 مرحله گرفته شد. اطلاعات جمع‌آوری‌شده با استفاده از روش‌های آماری توصیفی و استنباطی و سطح معنی‌داری 05/0>pمورد تجزیه‌وتحلیل قرار گرفت. یافته ها: تحلیل داده ها نشان داد که سطوح کراتین کیناز و لاکتات دهیدروژناز بلافاصه و دو ساعت پس از فعالیت ورزشی منتخب، در هر دو گروه مکمل و دارونما افزایش معنی داری داشته (05/0>p)، ولی سطوح آلانین آمینو ترانسفراز و آسپارتات آمینو ترانسفراز تغییر معنی داری نداشته است (05/0<p). مصرف مکمل CGT باعث کاهش معنی دار پاسخ کراتین کیناز و لاکتات دهیدروژناز به HIIE در زمان های بلافاصه و 2 ساعت پس از فعالیت شد (05/0> p). با این حال، مصرف مکمل CGT تاثیر معنی داری بر تغییرات آلانین آمینوترانسفراز و آسپارتات آمینوترانسفراز بلافاصله و 2 ساعت پس از HIIE نداشت (05/0<p). نتیجه‌گیری: به طور کلی نتایج نشان داد که مکمل دهی کوتاه مدت CGT از آسیب عضلانی ناشی از فعالیت ورزشی شدید جلوگیری می کند.

کلیدواژه‌ها


عنوان مقاله [English]

The effect of combined creatine, glutamine, and turin supplementation on the response to muscle and liver damage induced by high intensity interval exercise in trained men

نویسندگان [English]

  • Ali Moeini Najafabadi 1
  • Farhad Rahmani-Nia 2
  • Bahman Mirzaei 2
  • Ali Eslampour 1
1 MSc of Applied Exercise Physiology, Faculty of Sport Sciences, University of Guilan, Rasht, Iran.
2 Professor, Department of Exercise Physiology, Faculty of Sport Sciences, University of Guilan, Rasht, Iran.
چکیده [English]

Background and Aim: CGT sport supplement is combined of three creatine, glutamine and taurine supplement that respectively formed 50, 30 and 20 percent of the total content of supplementation. The aim of this study was to investigate the effect of CGT supplementation on response of markers of muscle and liver damage (creatine kinase, lactate dehydrogenase, alanine aminotransferase and aspartate aminotransferase) to high intensity interval exercise in trained men. Materials and Methods: Nineteen trained men (age: 22.28±0.73 years; BMI: 22.35±1.66 kg/m2; fat percentage: 8.87±2.93 %) were randomly divided into two groups including CGT supplementation (n=9) and placebo (n=10). Supplementation group consumed CGT supplementation for 2 weeks up to 12 grams per day and placebo group consumed starch powder at same dose. Both groups performed HIIE protocol at pre and post-supplementation that contains the sequences. Blood samples were taken in 6 steps included before, immediately and 2 hours after the pre test, and the same steps in the post-test. The collected data were analyzed using descriptive and inferential statistics and significant level of pResults: Data analysis showed, creatine kinase and lactate dehydrogenase levels significantly increased immediately and two hours after the exercise in both supplement and placebo groups (p˂0.05). But there was no significant changes in alanine aminotransferase and aspartate aminotransferase levels. (p>0.05). CGT supplementation significantly decreased response of creatine kinase and lactate dehydrogenase to HIIE immediately and 2 hours after the activity (p˂0.05). However, CGT supplementation no significantly affected by changes in alanine aminotransferase and aspartate aminotransferase immediately and 2 hours after HIIE (p>0.05).
Conclusion: Generally, the results indicated that short-term CGT supplementation prevents from muscle damage induced by high intensity interval exercise.

کلیدواژه‌ها [English]

  • high intensity interval exercise
  • combining Creatine
  • Glutamine and Taurine (CGT) supplementation
  • muscle and liver damage
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