عنوان مقاله [English]
Background and Aim: Cardiac biomarkers can be considered as an indicatorto diagnose heart tissue damage and acute myocardial infarction. The purpose of this study was to evaluate the effect of an aerobic exercise with two different intensities on changes in myocardial injury indices including troponin I (CTnI) and creatine kinase MB (CK-MB) in non-athletic middle-aged men. Materials and Methods: Sixteen non-athletic and healthy middle-aged men (mean age 41.72 ± 6.71 years old, height 176.96 ± 5.77 cm and weight 74.77 ± 8.17 kg) were randomly selected forthisstudy in crossover design with 14 day wash out. Subjects were randomly assigned to one of two experimental groups (Moderate intensity group (MI): 8n and High intensity group (HI): 8n). Further, MI group and group HI, ran over a treadmill for thirty minutes with 60% VO2max and 75% VO2max respectively. Blood samples were taken before, immediately and 4 hours after exercise. Data were analyzed using repeated measure ANOVA and independent t-test with significance level was set as pResults: The results indicated that CK-MB significantly increased immediately and four hours after exercise as compared tobaseline in both groups of MI (p<0.001) and HI (p<0.001). However, the increase in cTnI level was significant only after 4 hours after exercise in both groups (p<0.001). In addition, the magnitude of increase in CK-MB (p=0.003) and CTnI (p=0.001) was significantly higher in the HI group than in the MI group, 4 hours after the exercise. Conclusion: According to the results of this study, both moderate and high severity exercises increased the cardiac injury biomarkers, but it seems that high intensity exercise could reults in more damage tomyocardialtissue.
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