تاثیرتمرین هوازی حاد با دو شدت متفاوت بر تغییرات شاخص‌های آسیب میوکارد در مردان میانسال غیرورزشکار

نوع مقاله: مقاله پژوهشی

نویسندگان

1 کارشناس ارشد فیزیولوژی ورزشی، دانشکده علوم تربیتی و روانشناسی، دانشگاه محقق اردبیلی، اردبیل، ایران.

2 دانشیار فیزیولوژی ورزشی، گروه تربیت بدنی و علوم ورزشی، واحد اردبیل، دانشگاه آزاد اسلامی، اردبیل، ایران.

3 دانشیار فیزیولوژی ورزشی، دانشکده علوم تربیتی و روانشناسی، دانشگاه محقق اردبیلی، اردبیل، ایران.

چکیده

زمینه و هدف: نشانگرهای  قلبی شاخص­هایی هستند که در تشخیص آسیب بافت قلب و انفارکتوس حاد میوکارد استفاده می­شوند. هدف از تحقیق حاضر ارزیابی تاثیر یک وهله تمرین هوازی با دو شدت‌ متفاوت بر تغییرات شاخص­های آسیب میوکارد شامل تروپونینI (CTnI) و کراتین کیناز MB (CK-MB) در مردان میانسال غیرورزشکار بود. روش تحقیق: شانزده مرد میانسال غیرورزشکار و سالم (با میانگین سنی 71/6±20/41 سال، قد 77/5±96/176 سانتی‌متر و وزن 17/8±07/74 کیلوگرم) به‌صورت تصادفی انتخاب و به روش همگذر با فاصله 14 روز در مطالعه شرکت کردند. آزمودنی­ها ابتدا به ‌طور تصادفی در یکی از دو گروه تجربی (هر کدام 8 نفر) تمرین با شدت متوسط ­(MI) تمرین با شدت بالا (HI) قرار گرفتند. گروه MI با شدت 60% حداکثر اکسیژن مصرفی و گروه HI با شدت 75% حداکثر اکسیژن مصرفی به مدت 30 دقیقه بر روی نوارگردان دویدند. نمونه‌های خونی قبل، بلافاصله و 4 ساعت بعد از فعالیت گرفته شد. از آزمون­های آماری آنالیز واریانس با اندازه­گیری های مکرر و t مستقل جهت تحلیل آماری داده­ها استفاده شد. سطح معنی­داری برابر 05/0>p بود. یافته­ ها: افزایش معنی­داری در میزان CK-MB بلافاصله و 4 ساعت بعد از تمرین نسبت به حالت پایه در هر دو گروه MI (001/0p<) و HI (001/0p<) مشاهده شد، درحالی که افزایش میزان cTnI فقط 4ساعت بعد از تمرین در هر دو گروه نسبت به حالت پایه و بلافاصله بعد معنی­دار بود (001/0>p). به علاوه، میزان افزایش CK-MB (003/0p=) و CTnI (001/0p=) در گروه HI نسبت به گروه MI، 4 ساعت بعد از تمرین به طور معنی­داربیشتر بود. نتیجه ­گیری: بنابر نتایج تحقیق هر دو شدت متوسط و بالا باعث افزایش نشانگرهای آسیب قلبی می شوند، ولی به نظر می رسد تمرین با شدت بالا آسیب بیشتری به بافت میوکارد قلبی می زند.

کلیدواژه‌ها


عنوان مقاله [English]

The effect of two different intensities of aerobic exercise on myocardial injury Biomarkers in non-athletes middle-aged males

نویسندگان [English]

  • Azimeh Mohayyer Giglou 1
  • Babak Nakhostin Roohi 2
  • Lotfali Bolboli 3
1 Msc in Exercise Physiology, Faculty of Educational Sciences and Psychology, Mohaghegh-Ardabili University, Ardabil, Iran.
2 Associate Professor Exercise Physiology, Department of Physical Education & Sport Science, Ardabil Branch, Islamic Azad University, Ardabil, Iran.
3 Associate Professor Exercise Physiology, Faculty of Educational Sciences and Psychology, Mohaghegh-Ardabili University, Ardabil, Iran.
چکیده [English]

Background and Aim: Cardiac biomarkers can be considered as an indicatorto diagnose heart tissue damage and acute myocardial infarction. The purpose of this study was to evaluate the effect of an aerobic exercise with two different intensities on changes in myocardial injury indices including troponin I (CTnI) and creatine kinase MB (CK-MB) in non-athletic middle-aged men. Materials and Methods: Sixteen non-athletic and healthy middle-aged men (mean age 41.72 ± 6.71 years old, height 176.96 ± 5.77 cm and weight 74.77 ± 8.17 kg) were randomly selected  forthisstudy in crossover design with 14 day wash out. Subjects were randomly assigned to one of two experimental groups (Moderate intensity group (MI): 8n and High intensity group (HI): 8n).  Further, MI group and group HI, ran over a treadmill for thirty minutes with 60% VO2max and 75% VO2max  respectively. Blood samples were taken before, immediately and 4 hours after exercise. Data were analyzed using repeated measure ANOVA and independent t-test with significance level was set as pResults: The results indicated that  CK-MB significantly increased immediately and four hours after exercise as compared tobaseline in both groups of MI (p<0.001) and HI (p<0.001). However, the increase in cTnI level was significant only after 4 hours after exercise in both groups (p<0.001). In addition, the magnitude of increase in CK-MB (p=0.003) and CTnI (p=0.001) was significantly higher in the HI group than in the MI group, 4 hours after the exercise. Conclusion: According to the results of this study, both moderate and high severity exercises increased the cardiac injury biomarkers, but it seems that high intensity exercise could reults in more damage tomyocardialtissue.

کلیدواژه‌ها [English]

  • Aerobic exercise
  • Myocardial injury
  • MB creatine kinase isoenzymes
  • Troponin I

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