عنوان مقاله [English]
Background and Aim: Nesfatin-1 and neuropeptide Y are anti-appetite and the appetite hormones that play and important roles in energy balance and obesity. The aim of this study was to assess the effects of 12 weeks resistance training on serum levels of nesfatin-1 and neuropeptide Y in sedentary obese men. Materials and Methods: In this quasi-experimental study, 30 men aged between 48 to 60 years with BMI≥30 kg/m2, were randomly allocated to the resistance training and control groups. The training program consists of 12 weeks of resistance training, 3 sessions a week, 3 sets with 10 to 13 reps per session and with the intensity of 50-75% of one repetition maximum and 60-90 seconds rest. Every four weeks, one repetition maximum was calculated and the weights were adjusted again. Before and 48 hours after the 12 weeks exercise, measurement of nesfatin-1 and neuropeptide Y were performed. Repeated measures ANOVA was used for statistical analysis at significance level of p<0.05. Results: The results revealed that after 12 weeks resistance training, significant changes were not observed in the levels of nesfatin-1 (p=0.59) and cortisol (p=0.60). The levels of neuropeptide Y significantly (p=0.01). Also, a significant reduction in body mass index (p=0.02), body fat percent (p=0.01) and waist circumference (p=0.001) was observed in training group (p<0.05). The results showed that nesfatin-1 concentration did not change significantly in obese people after 12 weeks of resistance training. Conclusion: The type, severity and duration of this type of training is not enough to make a difference in these variables. There was also a significant increase in levels of neuropeptide Y, which represents the negative energy balance in subjects in resistance group.
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