عنوان مقاله [English]
Background and Aim: the reduction of Relaxin in menopause is one of the factors that cause physiological changes in women. Due to the lack of information about the effect of exercise training on the concentration of Relaxin, the aim of this research was to study the effect of different intensities of resistance and aerobic training on serum relaxin levels in ovariectomized rat. Materials and Methods: In this experimental study, 60 female rats average weight (230 ± 10 grams) were randomly assigned in to 6 groups of 10, including: ovariectomy, ovariectomy +high intensity resistance training, ovariectomy + low intensity resistance training, ovariectomy + intense intermittent swimming training, Ovariectomy + Continuous swimming training and Sham group. First, the animals became ovariectomized and after a week, the rats in the exercise group performed selected training 3 sessions per week for 8 weeks. Afterwards, the levels of serum relaxin were measured by ELISA method. Data analysis was performed using ANOVA test and the significant level was set at (p<0.05). Results: Serum relaxin concentration showed significant increase after 8 weeks of training as compared to the other groups as: control group, sham group (p=0.0001), intensive resistance training group (p=0.0001) and intensive exercise group (p=0.002) , however, no significant changes were observed in the continuous swimming training group (p=0.10) and low intensity resistance training group (p=0.43). Conclusion: Relaxin showed positive effects on various tissues of the body, this hormone decreases during menopause, but with high intensity exercise, the concentration of this hormone will increase.
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