The effect of high intensity interval training and spirulina supplementation on levels of angiopoietin-like proteins 3-4 and lipid profile in obese elderly women

Articles in Press

Document Type : Original Article

Authors

1 Assistant Professore at Department of Sport Sciences, Faculty of Literature and Humanities, University of Zabol, Zabol, Iran.

2 Associate Professore at Department of sport sciences, Faculty of Educational /Sciences and Psychology, University of Sistan and Baluchestan, Zahedan, Iran.

3 MSc of Exercise Physiology, Faculty of Educational Sciences and Psychology, University of Sistan and Baluchestan, Zahedan, Iran.

10.22077/jpsbs.2024.8315.1921

Abstract

Background and Aim: Angiopoietin-like proteins type 3 (ANGPTL3) and 4 (ANGPTL4) are emerging regulators of fat metabolism that play a role in obesity-related diseases such as cardiovascular diseases. The aim of this research was to investigate the effect of eight weeks of high intensity interval training (HIIT) with spirulina supplementation on serum levels of ANGPTL3, ANGPTL4 and lipid profile in obese elderly women. Materials and Methods: This study is a randomized clinical trial with a pre-test and post-test design. A number of 60 obese elderly women (mean age: 60.72±6.24 years; body mass index: 31.20±3.53 kg/m2) were selected by purposive sampling method and randomly divided into four equal groups supplement + training, placebo + training, supplement and control. The training groups performed intensity interval training (three sessions per week) for eight weeks, while the supplement groups consumed two 500 mg spirulina capsules daily. Research variables were measured at the beginning and end of the study. The data were analyzed using analysis of covariance and Tukey's post hoc and using SPSS version 22 software at a significance level of p≤ 0.05. Results: After eight weeks of HIIT with spirulina consumption, the serum levels of ANGPTL3 (p<0.01), ANGPTL4 (p<0.001), triglyceride (p<0.001), weight (p<0.001) ) and body fat percentage (p<0.001) decreased in supplement + training, placebo + training and supplement groups. While the levels of total cholesterol (p<0.001) and low-density lipoprotein (p<0.001) showed a significant decrease and high-density lipoprotein (p<0.001) showed a significant increase only in supplement + training and placebo + training groups. Conclusion: It seems that HIIT and spirulina supplement regulate lipid metabolism and improve lipid profile and reduce the risk of cardiovascular diseases in obese elderly.

Keywords

Journal of Practical Studies of Biosciences in Sport

Articles in Press, Accepted Manuscript
Available Online from 04 December 2024

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