Document Type : Original Article
Authors
1 MSc in Exercise Physiology, Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran.
2 Associate Professor at Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran.
3 Associate Professor at Department of Exercise Physiology, Faculty of Educational Sciences and Psychology, University of Mohaghegh Ardabili, Ardabil, Iran.
Abstract
Background and Aim: The effects of different doses of garlic supplementation on coagulation times after an acute endurance exercise are likely to be varied. The aim of this study was to investigate the effects of different doses of garlic supplementation on partial thromboplastin time (aPTT) and prothrombin time (PT) after an acute endurance exercise in young athletic men. Materials and Methods: Fifteen healthy young active men in the competition stage (age 27.0±7.9 years; weight 73.9±6.4 kg; and VO2max 49.59±0.35 ml/kg/min) with at least three years of experience of regular exercise in 5000 m endurance running voluntarily participated in this study. The subjects took different doses of garlic (500,750 and 1000 mg) and starch (placebo) in four separate sessions. In each session, four hours after taking the supplement or placebo, the subjects performed 30 min of running on treadmill at the intensity of 65-85% of target heart rate. Three blood samples were taken before supplementation, before exercise and immediately after exercise. The repeated measures ANOVA and Bonferroni tests were used to analyze the difference between different doses of garlic after acute endurance exercise and the difference between each doses of garlic and placebo at p<0.05. Results: Three dosage of 500, 750 and 1000 mg garlic were significantly increased aPTT. However, after acute endurance exercise, the three dosages of garlic significantly decreased aPTT. Additionally, the aPTT was significantly more decreased with 500 mg compared to 1000 mg of garlic after acute endurance exercise. There were no significant difference in PT after acute endurance exercise between three different dosage of garlic. Conclusion: It seems that after an acute endurance exercise in active men, 500 mg of garlic is more effective dose for reducing aPTT.
Keywords
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