Document Type : Original Article
Authors
Assistant Professore in Exercise Physiology, Department of Sport Sciences, Faculty of Literature and Humanities, University of Zabol, Zabol, IRAN.
Abstract
Background and Aim: Taking some anti-inflammatory supplements can be effective in reducing inflammation caused by intensity activities. The aim of the present study was to compare the response of netrin-1, TNF-𝛼 and IL-17 to acute continuous and intensity interval exercises after short-term quercetin supplementation in active girls. Materials and Methods: Fourty active girl students (average age: 21.3±61.03; body mass index: 21.3±79.12 kg/m2) were selected purposefully and randomly divided into four groups: continuous + supplement, interval + supplement, continuous + placebo and interval + placebo. Participants took quercetin supplement (1000 mg daily) or placebo for two weeks, and at the beginning and end of the two weeks, there was an acute continuous exercise and intensity interval exercise were implemented. Blood sampling in four stages; In the beginning and after two weeks of supplementation (before and after exercise) were done. The results were extracted using analysis of variance with repeated measures, one-way analysis of variance and post hoc LSD at a significant level (P≤0.05). Results: Continuous and interval exercises caused a significant decrease in the netrin-1 (p=0.01 and p=0.001, respectively) and increase in the TNF-𝛼 (p=0.01 and p=0.01, respectively). While, two weeks of quercetin supplementation was associated with a non-significant decrease in the netrin-1 (p=0.19 and p=0.32, respectively) and increase in the TNF -𝛼 (p=0.54 and p=0.16 respectively) in response to continuous and interval exercises. Also, there was no significant difference in netrin-1 (p=0.18) and TNF-𝛼 (p=0.42) values between continuous and interval groups. Finally, IL-17 response to interval and continuous acute exercises, before and after supplementation, did not show any significant difference (p=0.14). Conclusion: Short-term use of quercetin supplement by improving the inflammatory condition prevents inflammation caused by interval and continuous acute exercises in active girls.
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