Document Type : Original Article
Authors
1 Assistant Profesor Department of Sport Sciences, Faculty of Humanities and Social, Ardakan University, Ardakan, Iran
2 Department of Physical Education and sport science, Technical and Vocational University (TVU), Tehran, Iran.
3 Department of Sport Sciences, Faculty of Humanities and Social, Ardakan University, Ardakan, Iran
Abstract
Background and Aim:The use of medicinal plants along with exercise especially in obese people has received much attention due to the modulation of inflammatory and oxidative responses. Therefore, the aim of this study was to investigate the effect of eight weeks of HIIT and green tea supplement on serum levels of AChE, Aβ42 and MDA in untrained obese elderly men. Materials and Methods: For this purpose, 48 obese elderly men (average age 65.42±3.16 years and body mass index 30.93±1.15 kg/m2) were randomly divided into four groups of 12 people including HIIT, supplement green tea, HIIT+ green tea supplement and control- placebo. HIIT training was carried out for eight weeks and 3 sessions per week. Green tea supplement in the form of 6 capsules per day in the amount of 450 mg was received by the target groups. Testing was done 48 hours before and after the last training session. AChE and AB42 were measured by ELISA and MDA by TBA method. Results were extracted using analysis of covariance and Tukey's post hoc tests at a significance level of p<0.05. Result: The most significant changes (decrease) in body mass index (p=0.011, 3.50%) and percent body fat (p=0.0001, 11.07%); and a significant increase in maximum oxygen consumption (p=0.023, 9.22%) was observed in the HIIT+ green tea group.The combined effect of HIIT and green tea supplementation caused a significant decrease in AChE (p=0.0001, 19.91%), Aβ42 (p=0.0001, 27.99%), and MDA (p=0.014, 28.59%). The main effect of HIIT significantly decreased AChE (p=0.024, 15.67%), Aβ42 (p=0.013, 16.22%) and MDA (p=0.010, 14.33%); and green tea supplement caused a significant decrease in Aβ42 (p=0.023, 6.19%). Conclusion: The combined intervention of HIIT with green tea supplement compared to the effect of each one alone, causes a further reduction of inflammatory and oxidative indices in obese elderly men.
Keywords
)