Document Type : Original Article
Authors
1 Assistant professor, Department of physical education and Sport Sciences, school of Human Sciences, University of Zabol, Zabol, Iran
2 Assistant professor, Department of Physical Education and Sport Sciences, Faculty of Literature and Humanities, University of Neyshabur, Neyshabur, Iran
3 Assistant professor, Department of Physical Education and Sport Science, Technical and Vocational University (TVU), Tehran, Iran
4 PhD Student in Exercise Physiology, Department of Exercise Physiology, Faculty of Physical Education and Sport Sciences, University of Tabriz, Tabriz, Iran
Abstract
Background and Aim: Studies have shown that gremlin-1 is involved in adipose tissue dysfunction in obesity, type 2 diabetes and metabolic disorders. The aim of this study was to investigate the effect of high-intensity functional training on gremlin-1 levels and insulin resistance in overweight and obese women. Materials and Methods: In this semi-experimental study, 20 overweight and obese women were randomly divided into two groups of high-intensity functional training (n=10) and control (n=10). The subjects of the training group performed high-intensity functional exercises three times a week for eight weeks. In order to measure fasting glucose, insulin resistance and gremlin 1 before and after the intervention, blood samples were taken from the subjects. To analyze the data in SPSS software version 16, analysis of covariance and paired t tests were used at a significance level of 0.05. Results: After eight weeks of high-intensity functional training, body weight (p=0.001), body mass index (p=0.001), fat percentage (p=0.001) and fasting glucose (p=0.001) was significantly reduced in the experimental group compared to the control group. Also, insulin resistance index (p=0.001) and gremlin 1 concentration (p=0.03) decreased significantly in the experimental group compared to the control group. Conclusion: The results of the present study showed that high-intensity functional training in overweight and obese women leads to a decrease in gremlin-1 levels and insulin resistance. Therefore, these types of exercises can be used as exercise interventions in controlling and reducing complications related to overweight and obesity.
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