Introduction and purpose: obesity and overweight are a metabolic disorder that affects the levels of adipose tissue in this disorder. The aim of the present study was to the effect of eight weeks of intense Continuous endurance, resistance, and High intensity interval training on SLIT-2 and UCP-1 gene expression in non-obese rats.
methodology; In the current study, 36 obese Wistar rats, eight weeks old and weighing 325 ± 40 grams, were randomly divided into four groups; Continuous Endurance (10 heads), resistance (8 heads), High intensity interval training (10 heads) and control (8 heads) were divided. For eight weeks, the rats of the experimental groups performed five sessions of endurance training with an intensity of 70-80% of the maximum speed, resistance with an intensity of 50-120% of the body weight and intense intervals with an intensity of 85-90% of the maximum speed, and each 5% per week was added to the intensity of the exercises. Real Time-PCR method was used to measure SLIT-2 and UCP-1 gene expression.
Findings; The results of the present study showed that all three models of Continuous endurance, resistance and High intensity interval training caused a significant increase in the expression of SLIT-2 (P=/001) and UCP-1 (P=/001) compared to the control group, but there was no difference between the experimental groups. Not observed (P= 0.999).
discussion; Based on the results of this research, it is suggested to use Continuous endurance, resistance and High intensity interval training with increasing SLIT-2 and UCP-1 gene expression, which are factors influencing lipolysis and are effective in increasing lipolysis, in order to lose weight.