Hossain Jokar; Sirous Farsi; Mehran Ghahramani
Abstract
Background and Aim: Role of exercise training and antioxidant supplements has been reported in the kidney tissue, but their interactive effect is still not well understood. This research examines the effect of eight weeks of resistance training and zinc supplementation on tumor necrosis factor alpha ...
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Background and Aim: Role of exercise training and antioxidant supplements has been reported in the kidney tissue, but their interactive effect is still not well understood. This research examines the effect of eight weeks of resistance training and zinc supplementation on tumor necrosis factor alpha (TNF-α) and C -reactive protein (CRP) of kidney tissue in rats following complete unilateral ureteral obstruction. Materials and Methods: In this experimental study, 32 male Sprague-Dawley rats with an age range of 12-16 weeks and a weight range of 220-250 grams were selected; the rats ureters were completely obstructed during surgery, were randomly divided into four groups including: nephrectomy control, Zinc supplementation, resistance training, and resistance training + Zinc supplementation. Moreover, to investigate the effects of nephrectomy, eight healthy rats were assigned in the healthy control group and eight one that underwent surgery with no kidney obstruction were assigned in the sham group. The resistance training groups performed climbing with an intensity of 30-100% of their body weight three times a week for eight weeks. The Zinc supplementation groups received 30 mg/kg/w Zinc supplement orally each day. To analyze the data, one-way analysis of variance with Tukey’s post hoc test were used at p<0.05 level. Results: The results showed significant reduction in TNF-α and CRP levels in both training and supplementation groups than the non-training (control) groups (p=0.001). Also, the interaction of training and supplementation was significant in reducing CRP levels in rats following unilateral ureteral obstruction (p=0.001). Conclusion: It appears that resistance training and Zinc supplementation both individually and interactively, have synergistic effects on reducing inflammatory factors; however, further studies are needed about the interactive effect of these factors on TNF-α levels.
Ali-Reza Ghamari; Mehran Ghahramani; Nahid Mohammadi javid
Abstract
Background and Aim: An inactive lifestyle is associated with an increased risk of obesity, increased insulin resistance, and cardiovascular diseases while nutritional interventions along with the implementation of exercise programs, can be considered as a modify controlling of these impairments. The ...
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Background and Aim: An inactive lifestyle is associated with an increased risk of obesity, increased insulin resistance, and cardiovascular diseases while nutritional interventions along with the implementation of exercise programs, can be considered as a modify controlling of these impairments. The aim of this study was to compare the effect of high intensity interval (HIIT) and moderate intensity continuous (MICT) training along with peppermint extract consumption on body composition and serum level of Nesfatin-1 in overweight men. Materials and Methods: Forty eight non-athletes healthy overweight men 25 to 35 years old, body mass index of 25 to 30 kg/m2 were purposefully selected and randomly divided into six groups including: 1) placebo, 2) peppermint, 3) MICT + placebo, 4) HIIT + placebo, 5) MICT + peppermint, and 6) HIIT + peppermint (n=8 in each group). Interventions were performed for six weeks. MICT and HIIT protocols were implemented with an intensity of 60-75% and 90-100% of the maximum heart rate of the reserve, respectively, with repetition of three sessions a week, and the supplement groups also consumed 50 microliters of peppermint essential oil in combination with 500 ml of water. Data were analyzed through SPSS18 using a mixed-design analysis of variance in a six groups and two times at p≤0.05 level. Results: The MICT and HIIT (both) significantly reduced the percentage of body fat in overweight men (p<0.05); however, there was no significant difference in the amount of lean body mass and Nesfatin-1 (p>0.05). Conclusion: Six-week of intervention with consumption of peppermint essential oil (with consumed dose) separately and in combination with MICT and HIIT were not enough for improvement of Nesfatin-1 and lean body mass in overweight men.
