Document Type : Original Article
Authors
Abstract
Background and Aim: Based on the limited and inconsistent results in regarding to the effects of intense exercise on inflammatory markers and muscle damage in adolescents, the aim of this study was to examine the response and relationship between some inflammatory markers and muscle damage in 14-16 years old boys in response to incremental physical activity. Materials and Methods: Twenty-four healthy 14-16 years old boys volunteered and divided in two groups as exercise (n=12) and control (n=12) groups. The exercise group performed incremental modified Balke protocol physical activity, according to the defined protocol. In order to examine the levels of plasma fibrinogen, Serum CRP and CPK blood samples were collected in baseline and immediately 2 minutes after incremental physical activity in trained group and also in baseline and 48 hours later in the controls group. To statistical analysis the dependent t-test, independent t-test, Pearson's correlation coefficient and beta coefficient were used and the significant level set at pResults: Serum CRP (p=0.01), CPK (p=0.01) and plasma fibrinogen (p=0.01) levels significantly increased immediately after intense exercise in the exercise group (p<0.01). Moreover, the relationship between variables showed, significant correlation between plasma fibrinogen with Serum CRP (r=0.661 p<0.016) and plasma fibrinogen with Serum CPK (r=0.617, p< 0.011) in the exercise group. Conclusions: According to results of this study the inflammatory markers and muscle damage indices were affected by intense aerobic exercise in adolescents, which indicates the presence of inflammation and muscle damage in response to intense aerobic exercise.
Keywords
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