Document Type : Original Article
Authors
1 PhD Student in Exercise Physiology, Facculty of Sport Sciences, University of Birjand, Birjand, Iran.
2 Professor at Department Exercise Physiology, Faculty of Sport Sciences, Uiversity of Birjand, Birjand, Iran.
3 Associate Professor at Department of General Courses, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Abstract
Background and Aim: NAFLD disease is strongly associated with insulin resistance in the liver and surrounding tissues, such as skeletal muscles and fat tissue, and regular physical exercise can be effective on human health and disease prevention and even treatment. The aim of the present study was to compare the effect of intense intermittent exercise and continuous aerobic exercise on the serum levels of glucagon-like peptide-1 receptor and fetoin A and insulin sensitivity in male rats with non-alcoholic fatty liver caused by a high-fat diet. Materials and Methods: The research method was experimental. 40 male desert rats aged 6-8 weeks with a weight between 150 and 180 grams were prepared and randomly divided into four groups (10 rats in each group) including intense intermittent exercise (80-95% of consumption). Moderate endurance exercise (50-60% of dietary intake), control (fatty liver disease) and healthy control (standard diet). were divided Sports training for 8 weeks and 5 sessions a week, for any income. For the results, statistical tests of one-way analysis of variance and Tukey were used at the significance level of P<0.05. Results: Intense intermittent training (P=0.008) and moderate continuous training (P=0.033) decreased the serum level of Fetoin-A, and there was no significant difference between the two training effects (P<0.05). Intense intermittent training (P=0.008) and moderate continuous training (P=0.003) increased serum glucagon-like peptide-1 receptor and there was no significant difference between the two training effects (P<0.05). Intense intermittent training (P=0.007) and moderate continuous training (P=0.013) increased insulin sensitivity and there was no significant difference between the two training effects (P<0.05). Conclusion: Intense intermittent and continuous aerobic exercises improved fetoin A levels, glucagon-like peptide-1 receptor serum levels, and insulin sensitivity; In addition, both types of exercise have the same effect.
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