Document Type : Original Article
Authors
1 Student, Faculty of Physical Education and Sports Sciences, Department of Physical Education, Shahrood University of Technology, Semnan, Iran.
2 Associate Professor at Departeman of Exrecise Physiology, Faculty of Physical Education and Sports Sciences, Shahrood University of technology, Shahrood, Iran.
3 Instructor of Sports Physiology Department, Faculty of Physical Education and Sports Sciences, Shahrood University of technology, Shahrood, Iran
Abstract
Introduction and purpose: The aim of this study was to investigate the effect of aerobic exercise and synbiotic supplementation on arterial stiffness and CRP in postmenopausal women with type 2 diabetes.
Materials and methods: In this semi-experimental study, 39 women with type 2 diabetes were randomly divided into three groups: aerobic exercise + placebo, aerobic exercise + synbiotic supplement, and synbiotic supplement. The duration of the exercise program was12 weeks (three sessions per week, the main part of the exercise in the first session consisted of 25 minutes of activity with an intensity of 40-45% of the maximum reserve heart rate, and every two weeks, 5 minutes were added to the duration and 5% to the intensity of the activity. Subjects in the supplement group consumed onesynbiotic capsule with (1x109CFU) one hour after having lunch. ANOVA test and correlated t-test was used to check the inter-group difference and intra-group difference of the subjects.
Findings: Intra-group results showed that ABI increased significantly in the group of aerobic exercise + placebo (P=0.03) and aerobic exercise + synbiotic supplement (P=0.028). Also, ankle physical health index (CAVI) in the group of aerobic exercise+placebo (P=0.002) and aerobic exercise+synbiotic supplement (P=0.022), C reaction in all 3 groups of aerobic exercise+placebo (P=0.001) Aerobic exercise + synbiotic supplement (P=0.0001) and synbiotic supplement group (P=0.002) showed a significant decrease. Serum levels of fasting glucose, insulin, insulin resistance index, BMI and body percent were also decreased in all 3, but this rate was reduced. The results of ANOVA did not show any significant difference in the research groups in ABI (P=0.292), CAVI (P=0.303), CRP (P=0.483), insulin (P=0.730).
Discussion and conclusion: It seems that aerobic exercise and consumption of synbiotics in postmenopausal women with type 2 diabetes can be effective in improving arterial stiffness and C-reactive protein indices
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