Document Type : Original Article
Authors
1 MS.c in Exercise Physiology, Department of Sport Sciences, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran.
2 Assistant Professor, Department of Sport Sciences, Bojnourd Branch, Islamic Azad University, Bojnourd, Iran.
Abstract
Background and Aim: Physical activity and exercise has been introduced as one of the ways to prevent cognitive decline due to aging. Thus purpose of the present study was to investigate the effect of 12 weeks step-aerobics training on amyloidβ-42 (Aβ42) and mental status of elderly women. Materials and Methods: Based on this quasi-experimental, 24 old women, 60 to 70 years were selected and divided randomly into experimental (n=12) and control (n=12) groups. The experimental group performed step-aerobics training with an intensity of 60 to 70% of maximal heart rate reserve, three sessions per week for 12 weeks. Plasma Aβ42 level was measured with Elisa kit and mental status determined using of MMSE questionnaire scale. Repeated measures analysis of variance and independent t-tests were used to compare the variables within group or between group respectively with the significant level of p<0.05. Result: There was a significant difference between the mean changes in plasma levels of Aβ42 in old women at pre-test, 8th week and 12th week (F=6.67, p=0.009) of training; whereas it was significantly lower at 12th weeks of training than pre-test (p=0.01). However, no significant difference was found between MMSE score in different stages (F=0.63, p=0.46). Conclusion: These results indicate the beneficial effects of long-term step-aerobics training on plasma Aβ42 levels in elderly women, and it seems that due to increase the length of the training period, it could be observed an improvement in cognitive function at this age group.
Keywords
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