Document Type : Original Article
Authors
1 MS.c in Exercise Physiology, Faculty of Sport Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran
2 Assistant Professor, Faculty of Sport Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
3 Full Professor of Sport Physiology, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
4 Ph.d Student of Exercise Physiology, Faculty of Sport Sciences, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
Abstract
Background and Aim: Acute exercise as a stressful physiological factor, may lead to immune response, and therefore can significantly increase the levels of inflammatory indices. The aim of this study was to compare the effect of one session of acute aerobic activity along vitamin C supplementation on pulmonary function of athletes with exercise induced bronchospasm. Materials and Methods: In this quasi-experimental study, 31 athletes were selected homogeneously according to Bruce treadmill test to determine VO2max above 45 ml/kg/min, further they randomly divided into two vitamin C (N=15) and control (N=15) groups. The subjects were asked to consume 500 mg/day vitamin C, three weeks during two-stage implementation of pre-test and post-test during exhaustive activity. The VC, FVC, FEV1, FEV1/FVC, PEF and MVV were measured using digital spirometer. The variables were statistically analyzed by paired-sample t test for intra-group comparison and ANCOVA for between groups comparison at a significant level of p<0.05, using SPSS19 software. Results: Consuming vitamin C, during three weeks had no significantly effect on VC (p=0.06); FVC (p=0.83); FEV1 (p=0.60); FEV1/FVC (p=0.69); PEF (p=0.18) and MVV (p=0.79), Moreover there was no significant difference between both experimental and control groups in VC (p=0.63); FVC (p=0.31); FEV1 (p=0.12); FEV1/FVC (p=0.06); PEF (p=0.36) and MVV (p=0.56). Conclusion: It seems that vitamin C had no significantly effect on mild exercise-Induced bronchospasmin athletes.
Keywords
Biltagi, M. A., Baset, A. A., Bassiouny, M., Kasrawi, M. A., & Attia, M. (2009). Omega - 3 fatty acids, vitamin C and Zn supplementation in asthmatic children: a randomized self‐controlled study. Acta Paediatrica, 98(4), 737-742.
Bonini, M., & Palange, P. (2015). Exercise-induced bronchoconstriction: new evidence in pathogenesis, diagnosis and
treatment. Asthma Research and Practice, 1(1), 1.
Baratpor, M., Dabidi Roshan, V., & Karimi, N. (2014). Tracking of changes insystemic inflammation following the Oxford
resistance exerciseand ginger supplement in male volleyball players. Journal of Practical Studies of Biosciences in Sport, 1(2), 21-34. [Persian]
Choudhuri, D., & Choudhuri, S. (2013). Effect of vitamin C supplementation on aerobic capacity, blood pressure and pulmonary functions in young male subjects. European Journal of Sports and Exercise Science, 2(2), 6-11.
Chubine S, Akbarnejad A, Barjian M, Kordri M. (2013). The effect of omega-3 supplementation on serum prostaglandin
E2 female athletes after one session exhaustive exercise. Biological Sciences Sports, 15, 121-133. [Persion]
Couto, M., Silva, D., Delgado, L., & Moreira, A. (2013). Exercise and airway injury in athletes. Acta Medica Portuguesa, 26(1), 56-60.
Denny, S. I., Thompson, R. L., & Margetts, B. M. (2003). Dietary factors in the pathogenesis of asthma and chronic obstructive pulmonary disease. Current Allergy and Asthma Reports, 3(2), 130-136.
Domej, W., Foldes-Papp, Z., Flogel, E., & Haditsch, B. (2006). Chronic obstructive pulmonary disease and oxidative stress. Current Pharmaceutical Bbiotechnology, 7(2), 117-123.
Fatemi, R., & Ghanbarzadeh, M. (2010). Assessment of air way resistance indexes and exercise-induced asthma after
a single session of submaximal incremental aerobic exercise. Journal of Human Kinetics, 25, 59-65.
Fogarty, A., Lewis, S. A., Scrivener, S. L., Antoniak, M., Pacey, S., Pringle, M., & Britton, J. (2003). Oral magnesium and vitamin C supplements in asthma: a parallel group randomized placebo-controlled trial. Clinical & Experimental Allergy, 33(10), 1355-1359.
Hallstrand, T. S., Moody, M. W., Wurfel, M. M., Schwartz, L. B., Henderson Jr, W. R., & Aitken, M. L. (2005). Inflammatory
basis of exercise-induced bronchoconstriction. American Journal of Respiratory and Critical Care Medicine, 172(6), 679-686.
Harik-Khan, R. I., Muller, D. C., & Wise, R. A. (2004). Serum vitamin levels and the risk of asthma in children. American
Journal of Epidemiology, 159(4), 351-357.
Hemilä, H. (2013). Vitamin C may alleviate exercise induced bronchoconstriction: a meta-analysis. BMJ Open Respiratory Medicine Research, 3(6), e002416.
Kazemi, M., Marandi, S. M., Movahedian Attar, A., Haghighatian, M., & Rezaee, Z. (2014). The effect of acute exercise on total antioxidant capacity and hydrogen peroxide in male Wistar rats. Journal of Practical Studies of Biosciences in Sport, 2(3), 29-37. [Persian]
Kelly, F. J. (2005). Vitamins and respiratory disease: antioxidant micronutrients in pulmonary health and disease. Proceedings of the Nutrition Society, 64(4), 510-526.
Kang, J., Chaloupka, E. C., Mastrangelo, M. A., Biren, G. B., & Robertson, R. J. (2001). Physiological comparisons among three maximal treadmill exercise protocols in trained and untrained individuals. European Journal of Applied Physiology, 84(4), 291-295.
Malo, J. L., Cartier, A., Pineau, L., L'Archevêque, J., Ghezzo, H., & Martin, R. R. (1986). Lack of acute effects of ascorbic acid on spirometry and airway responsiveness to histamine in subjects with asthma. Journal of Allergy and Clinical Immunology, 78(6), 1153-1158.
McAnulty, S. R., Nieman, D. C., Fox-Rabinovich, M., Duran, V., McAnulty, L. S., Henson, D. A., ... & Landram, M. J. (2010). Effect of n-3 fatty acids and antioxidants on oxidative stress after exercise. Medicine & Science in
Sports & Exersice, 42(9), 1704-11.
Messan, F., Marqueste, T., Akplogan, B., Decherchi, P., & Grélot, L. (2012). Exercise-induced bronchospasm diagnosis in sportsmen and sedentary. International Scholarly Research Network Pulmonology, 1-7.
Mickleborough, T., & Lindley, M. (2014). The effect of combining fish oil and vitamin C on airway inflammation and hyperpnea-induced bronchoconstriction in asthma. Journal of Allergy Therapy, 5(4), 1-10.
Mickleborough, T. D., Lindley, M. R., Ionescu, A. A., & Fly, A. D. (2006). Protective effect of fish oil supplementation on exercise-induced bronchoconstriction in asthma. Chest Journal, 129(1), 39-49.
Nadi, E., Tavakoli, F., Zeraati, F., Goodarzi, M. T., & Hashemi, S. H. (2012). Effect of vitamin C administration on leukocyte vitamin C level and severity of bronchial asthma. Acta Medica Iranica, 50(4), 233-238.
Parsons, J. P., Hallstrand, T. S., Mastronarde, J. G., Kaminsky, D. A., Rundell, K. W., Hull, J. H., & Anderson, S. D. (2013).
An official American thoracic society clinical practice guideline: exercise-induced bronchoconstriction. American Journal
of Respiratory and Critical Care Medicine, 187(9), 1016-1027.
Rabiee, M.A., GharariArefi, R., Ghanbarzadeh, M., Habibi, A., Marashiyan, H. (2013). Revalence of respiratory tract obstruction in rofessional foreign wrestlers. Sport in Biomotor Sciences, 2(8), 32-40. [Persian]
Rahman, I., Biswas, S. K., & Kode, A. (2006). Oxidant and antioxidant balance in the airways and airway diseases. European Journal of Pharmacology, 533(1), 222-239.
Romieu, I., Sienra-Monge, J. J., Ramírez-Aguilar, M., Téllez-Rojo, M. M., Moreno-Macías, H., Reyes-Ruiz, N. I., & Hernández-Avila, M. (2002). Antioxidant supplementation and lung functions among children with asthma exposed to
high levels of air pollutants. American Journal of Respiratory and Critical Care Medicine, 166(5), 703-709.
Schwartz, J., & Weiss, S. T. (1994). The relationship of dietary fish intake to level of pulmonary function in the first National Health and Nutrition Survey (NHANES I). European Respiratory Journal, 7(10), 1821-1824.
Tari, M., Falah Mohamadi, Z., Dabidi Roshan, V., Olyaei M. (2009). Effects of aerobic training with bicycle ergometer on FEV1 and FVC, exercise tolerance, and shortness of breath in Chemical injured lung. Olympics, 1(45), 19-32. [Persian]
Tartibian, B., Maleki, B. H., & Abbasi, A. (2010). The effects of omega-3 supplementation on pulmonary function
of young wrestlers during intensive training. Journal of Science and Medicine in Sport, 13(2), 281-286.
Tecklenburg, S. L., Mickleborough, T. D., Fly, A. D., Bai, Y., & Stager, J. M. (2007). Ascorbic acid supplementation attenuates exercise-induced bronchoconstriction in patients with asthma. Respiratory Medicine, 101(8), 1770-1778.
Toorang, F., Djazayery, A., Jalali, M., Eshraghian, M. R., Farvid, M., Pooya, S. H., Chamari, M., Zaraei, M., & Fatahi, F. (2009). Effects of dietary omeg-3 fatty acid supplementation on HbA1c, total antioxidant capacity and superoxide dismutase and catalase activities in type-2 diabetic patients: A randomized clinical trial. Iranian Journal of Nutrition Sciences & Food Technology, 3(4), 1-8. [Persian]
The spirometry manual (2005). Center of Chemical deal with patients.
Ziaee, V., AhmadiNejad, Z., Farahi, A., Movahedi, M., & MansoorNia, M. (2006). Comparison of pulmonary function tests before and after exercise pro and semiprofessional basketball. Iran Journal of Basic Medical Science, 9(3), 172-177. [Persian]
ZunematKermani, Z., & Marefati, H. (2014). The prevalence of asthma and exercise-induced bronchoconstriction to specialized methods in elite endurance cyclists. Modern Olympics, 1(1), 37-45. [Persian]
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