Meysam Alipour-raz; Ali Golestani; Hossein TaheriChadorneshin
Abstract
Background and Aim: Intercellular adhesion molecule-1 (ICAM-1) and lipid profiles are the main factors in the occurrence of atherosclerosis and inflammatory diseases. Therefore, the purpose of current study was to investigate the effects of eight weeks of combined trainings (Resistance - Aerobic) along ...
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Background and Aim: Intercellular adhesion molecule-1 (ICAM-1) and lipid profiles are the main factors in the occurrence of atherosclerosis and inflammatory diseases. Therefore, the purpose of current study was to investigate the effects of eight weeks of combined trainings (Resistance - Aerobic) along with vitamin E supplementation on the serum levels of ICAM-1 and lipid profiles in sedentary and overweight men. Materials and Methods: For this purpose, 32 healthy sedentary overweight men (body mass index, 26.69 ± 0.91 kg/m2) participated in this semi experimental study and were randomly divided into four equal groups (n=8) of control, supplementation, exercise + placebo, and exercise + supplementation. Participants used 400 IU of vitamin E per day for eight weeks. Concurrent exercise (Resistance - Aerobic) was performed for eight weeks, three sessions per week. Fasting blood samples were taken pre and post of study protocol. Analysis of covariance test was used to evaluate the data at a significance level of p<0.05. Results: No significant intra-group changes were observed in the serum level of ICAM-1, low density lipoprotein cholestrol and triglyceride (p>0.05). Despite this, high density lipoprotein cholestrol increased significantly in the training–supplementation group (p<0.05). There was no significant inter-group difference in ICAM-1 serum levels and lipid profile after interventions (p>0.05). Conclusion: The results of current study suggested that concurrent exercise training along with vitamin E supplementation had no effect on serum ICAM-1, but it improved aerobic power in sedentary overweight men.
Amin Ashofteh; Sadegh Cheragh-Birjandi; Hossein TaheriChadorneshin
Abstract
Background and Aim: Although exercise training and antioxidants improve brain health, interactive effect of resistance training and Royal jelly has not yet been well established. Therefore, the aim of the current study was to investigate the effect of resistance training along with Royal jelly supplementation ...
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Background and Aim: Although exercise training and antioxidants improve brain health, interactive effect of resistance training and Royal jelly has not yet been well established. Therefore, the aim of the current study was to investigate the effect of resistance training along with Royal jelly supplementation on hippocampal gene expression of nerve growth factor (NGF) and tyrosine kinase A (TrkA) receptor in rat model of Alzheimer’s disease. Materials and Methods: In this experimental study, 42 male Sprague-Dawley rats were injected by Trimethyltin (8 mg/kg/body weight). Then, the rats were randomly divided into 7 equal groups including control, resistance training, resistance training+100 mg/kg Royal jelly supplementation, resistance training+200 mg/kg Royal jelly supplementation, 100 mg/kg Royal jelly supplementation, 200 mg/kg Royal jelly supplementation and sham groups. The resistance training protocol was performed for 8 weeks, three sessions per week at intensity to 30-100% of their body weight. Gene expression was assessed using Real-Time PCR and all primers were designed by Allele IDv7.8 software. Data were analyzed using two-way analysis of variance and Bonferroni post hoc tests at the p<0.05. Results: The resistance training induced a significant increase in NGF expression (p= 0.001). Moreover, 100 and 200 mg/kg Royal jelly supplementation, resistance training+100 and 200 mg/kg Royal jelly supplementation resulted in a significant increases in expression of NGF and TrkA receptor (p=0.001). In addition, the effect of royal jelly supplementation on NGF and TrkA receptor expression was dependent on its dosage, where the dose of 200 mg/kg was significantly higher than the dose of 100 mg/kg (p=0.001). Conclusion: Both resistance training and Royal jelly supplementation, alone and synergistically, can increase neurotrophins expression in the hippocampus of Alzheimer’s rats; however higher dose of Royal jelly supplementation may induce more improvement.
Mahboobe Ajam Zibad; Hossein TaheriChadorneshin; Seyed Hosein Abtahi Eivary
Abstract
Background and Aim: Studies have reported conflicting results regarding the acute effects of exercise on inflammatory, oxidative stress and muscle damage parameters. Therefore, this study aimed to investigate the effect of acute resistance exercise on serum levels of tumor necrosis factor alpha (TNF-α), ...
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Background and Aim: Studies have reported conflicting results regarding the acute effects of exercise on inflammatory, oxidative stress and muscle damage parameters. Therefore, this study aimed to investigate the effect of acute resistance exercise on serum levels of tumor necrosis factor alpha (TNF-α), as a marker of inflammation, malondialdehyde (MDA), as a marker of oxidative stress, and levels of lactate dehydrogenase (LDH) and creatine kinase (CK), as two markers of muscle damage. Materials and Methods: For this purpose, 20 healthy and inactive women (age, 21.55+1.56 year; BMI, 21.68+3.26 kg/m2) were randomly divided into acute resistance exercise and control groups. The subjects performed one bout of acute resistance exercise with 85% of one-repetition maximum (1RM) at 8 stations (bench press, leg press, seated rows, overhead press, seated leg press, arm extension, arm curls and calf raises), each exercise were done for 3 sets. Blood samples were taken before and immediately after exercise. TNF-α and MDA levels were measured using ELISA method by commercial kits. Moreover, LDH and CK were measured by photometric method. Paired sample t-test and independent t-tests were used to analyzed dependent variable within and between groups, respectively (p<0.05). Results: One bout of acute resistance exercise had significant increases (p=0.001) in serum levels of TNF-α and MDA. Also, serum levels of muscle damage parameters, LDH (p=0.03) and CK (p=0.001), showed significantly increases following acute resistance exercise. Conclusion: One bout of intense resistance exercise is associated with oxidative and muscle damage in inactive women, therefore adoption of training and nutritional approaches are essential when implementing with this kind of exercise.
