عنوان مقاله [English]
Background and Aim: Exercise training in hypoxic conditions may have different physiological effects on body systems that can be beneficial for athletes. The purpose of this study was the effects of 8 weeks of repetitive speed trainingin hypoxia and normoxia conditions on vascular endothelial growth factor (VEGF) in swimmers. Materials and Methods: This study is a semi-experimental research with pre-test and post-test which was performed on 30 women elite swimmers. The subjects were randomly divided into three groups including two experimental groups (training group in hypoxia and normoxia conditions) and control group. Training groups exercised 5 sessions per week including 2 training sessions on the stationary ergometer and 3 sessions in swimming pool for 8 weeks. Training protocols for both experimental groups was designed with the same intensity and duration (9 attempts for 30 seconds at 80% of maximum performance, with two minutes of rest) on swimming ergometer. The training of hypoxia group was performed in hypoxia condition stimulated 3500 meter altitude with %14 of Fio2. At this time, the control group only performed 5 normal swimming sessions per week. The vascular endothelial growth factor factors in all three groups were measured by ELISA before and after 8 weeks. By the SPSS software it is applied the one way ANOVA test at the significant level of p≤0.05 for extraction of results. Results: The mean post-test of VEGF was higher than pre-test in both groups of hypoxia (p<0.01) and normoxia (p<0.04) conditions, but these differences were not statistically significant between gruops (p>0.05). Conclusion: Hypoxia conditions induced by exercise protocols were not effective in increasing the VEGF, and it seems that the activating of this factor required more duration and intensity of training in this environment.
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